---
title: Does vitamin B6 (pyridoxine) help treat PMS symptoms? | Niyora
description: Yes, vitamin B6 appears to help. Over half of the 70 women studied showed considerable benefit, especially for headaches, bloating, and mood changes.
url: https://niyora.com/research/papers/the-management-of-the-premenstrual-syndrome-1977/
---

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- Does vitamin B6 (pyridoxine) help treat PMS symptoms?

Study, 1977

# Does vitamin B6 (pyridoxine) help treat PMS symptoms?

Yes, vitamin B6 appears to help. Over half of the 70 women studied showed considerable benefit, especially for headaches, bloating, and mood changes.

 Early or limited evidence

70 women with PMS, mean age 34.8 years

## What they did

Researchers gave 70 women with PMS doses of pyridoxine ranging from 40 mg to 100 mg daily and tracked how well it worked.

## What they found

Over half of the women had considerable benefit. It was particularly effective for headache, swelling, bloatedness, depression and irritability.

## What it means for you

Vitamin B6 may help many women with PMS, especially for water retention and mood symptoms. The study showed positive results and women tolerated it well, but it is unclear exactly how much benefit each dose level provided or how many women it did not help.

70

women studied

34.8

mean age in years

40-100 mg

pyridoxine daily

## About the study

Original title The management of the premenstrual syndrome Authors Graeme D. Kerr Journal Current Medical Research and Opinion Year 1977 Study design Study Participants 70 What was tested Pyridoxine (vitamin B6) in doses from 40 mg to 100 mg daily Read the paper [doi.org/10.1185/03007997709115298](https://doi.org/10.1185/03007997709115298)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Vitamin B6](https://niyora.com/research/topics/treatment-vitamin-b6/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Randomised trial, 1997

Does Vitex agnus castus work better than vitamin B6 for premenstrual tension syndrome?

Review, 2023

Can herbs and supplements help with PMS symptoms?

Randomised trial, 2007

Does bromocriptine or pyridoxine help reduce PMS symptoms?

Randomised trial, 2000

Does magnesium and vitamin B6 together help with anxiety-related premenstrual symptoms?

Randomised trial, 1989

Does vitamin B6 reduce PMS mood symptoms?

Randomised trial, 1987

Does vitamin B6 help premenstrual tension symptoms?

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