---
title: Can Periodin reduce premenstrual syndrome symptoms? | Niyora
description: In a small uncontrolled study, 24 women taking Periodin for 3 months reported a 52.3% decrease in symptoms, but without a control group we cannot be sure the
url: https://niyora.com/research/papers/the-possibility-for-treating-the-premenstrual-syndrome-with-periodin-2000/
---

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- Can Periodin reduce premenstrual syndrome symptoms?

Non-randomised trial, 2000

# Can Periodin reduce premenstrual syndrome symptoms?

In a small uncontrolled study, 24 women taking Periodin for 3 months reported a 52.3% decrease in symptoms, but without a control group we cannot be sure the improvement came from the supplement.

 Early or limited evidence

24 women with PMS in the premenopausal period, average age 44.7 years

## What they did

24 women with PMS took Periodin (a supplement containing vitamins, minerals, and plant extracts) at 1 to 2 capsules daily for 3 months. Symptoms were measured using a modified scoring system.

## What they found

After treatment, PMS symptoms decreased by 52.3% from baseline.

## What it means for you

While the symptom improvement was substantial, this study had no control group for comparison, making it unclear whether improvement was due to the supplement or other factors. The sample was small.

24

women studied

52.3%

symptom decrease

3 months

treatment duration

## About the study

Original title [The possibility for treating the premenstrual syndrome with Periodin] Authors Rachev E, Nalbanski B, Stamenov G Journal Akusherstvo i ginekologiia Year 2000 Study design Non-randomised trial Participants 24 What was tested Periodin (combination of polyvitamins, oligoelements and phytoextracts) Read the paper [https://pubmed.ncbi.nlm.nih.gov/10826332/](https://pubmed.ncbi.nlm.nih.gov/10826332/)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)

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