--- title: Does depression or panic disorder increase the risk of severe PMS? description: Yes. Women with panic disorder had much higher rates of severe PMS (43%) than women with depression (16%) or no mental health conditions (10%). url: https://niyora.com/research/papers/the-prevalence-of-premenstrual-dysphoric-disorder-in-patients-with-depressive-or-2022/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does depression or panic disorder increase the risk of severe PMS? Survey study, 2022 # Does depression or panic disorder increase the risk of severe PMS? Yes. Women with panic disorder had much higher rates of severe PMS (43%) than women with depression (16%) or no mental health conditions (10%). Early or limited evidence 159 women with PMS in three groups: 98 without psychiatric conditions, 31 with depression, and 30 with panic disorder ## What they did Cross-sectional study of 159 women with PMS divided into three groups: 98 with no psychiatric conditions, 31 with depression, and 30 with panic disorder. Researchers used screening tools to diagnose PMS and mental health conditions. ## What they found In women with no psychiatric conditions, 10% (n=10) had PMDD. In women with depression, 16% (n=5) had PMDD. In women with panic disorder, 43% (n=13) had PMDD. The researchers concluded that comorbid depression or panic disorder increases the prevalence of PMDD, especially panic disorder. ## What it means for you If you have panic disorder or depression, you may be at higher risk for severe PMS. The study shows an association but does not prove that one causes the other. The sample sizes in each group were small. 43% PMDD in women with panic disorder 16% PMDD in women with depression 10% PMDD in women without psychiatric conditions ## About the study Original title The prevalence of premenstrual dysphoric disorder in patients with depressive or panic disorder Authors Chochev Y, Iakimova R, Pandova M Journal European psychiatry : the journal of the Association of European Psychiatrists Year 2022 Study design Survey study Participants 47 What was tested None Open access Yes Read the paper [doi.org/10.1192/j.eurpsy.2022.1162](https://doi.org/10.1192/j.eurpsy.2022.1162) Original abstract Introduction: Premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS), affects 3-5% of the women of childbearing age. According to scientific literature, the prevalence of PMDD increases with age and among the psychiatric patient population as well, e.g. in women suffering depressive disorder (DD) or panic disorder (PD). Objectives: To estimate the prevalence of PMDD in women without psychiatric comorbidities and those with concomitant DD or PD. Methods: A cross-sectional non-interventional study that enrolled 159 women, divided in 3 groups: 1) 98 women (mean age 31.04 ± 6.31) with PMS and no psychiatric comorbidities; 2) 31 women with PMS and DD (mean age 39.4±7.21); 3) 30 women with PMS and PD (mean age 31.2±7.89). PMS was assessed by the PSST (Premenstrual Symptoms Screening Tool). DD and PD were diagnosed by MINI and a psychiatric evaluation. Descriptive and frequency statistics were performed. Results: Within the group without comorbidities mild PMS was present in 48% (N=47) of the cases, moderate - in 41,8% (N=41), and in 10,2% (N=10) of the cases PMDD was diagnosed. Within the group with comorbid DD 25,8% (N=8) had mild PMS, 58,1% (N=18) had moderate and 16,1% (N=5) had PMDD. Among the women with comorbid PD 56,7% (N=17) suffered moderate PMS, 43,3% (N=13) - PMDD and no mild cases were documented. Conclusions: The results demonstrate that comorbid DD or PD increases the prevalence of PMDD. It is considerably more common in patients with PD than those with DD. Disclosure: No significant relationships. Reproduced under CC-BY. ## Topics [Anxiety disorders and OCD](https://niyora.com/research/topics/comorbidity-anxiety-disorders/)[Major depressive disorder](https://niyora.com/research/topics/comorbidity-major-depression/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Anxiety and tension](https://niyora.com/research/topics/symptom-anxiety/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Non-randomised trial, 2008 Can the Sheehan Disability Scale measure whether treatments work? Study, 2026 Do anxiety and depression get worse before your period if you already have a mental health condition? Study, 2026 What are premenstrual syndrome and premenstrual dysphoric disorder? Review, 2014 Are mental health problems linked to gynecological conditions like PMS and PMDD? Cohort study, 2012 How quickly does fluoxetine start working for PMDD symptoms? Randomised trial, 2004 Does paroxetine controlled-release help PMDD symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗