---
title: Does magnesium with vitamin B help PMS symptoms? | Niyora
description: Yes. Magnesium citrate with vitamin B2 significantly decreased several PMS symptoms including anxiety, depression, resentment, tearfulness, and headache. Howe
url: https://niyora.com/research/papers/the-role-of-magnesium-in-the-treatment-of-premenstrual-syndrome-2020/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Library](https://niyora.com/research/library/)
- Does magnesium with vitamin B help PMS symptoms?

Survey study, 2020

# Does magnesium with vitamin B help PMS symptoms?

Yes. Magnesium citrate with vitamin B2 significantly decreased several PMS symptoms including anxiety, depression, resentment, tearfulness, and headache. However, blood magnesium levels did not change significantly.

 Early or limited evidence

65 women with premenstrual syndrome

## What they did

65 women with PMS were divided into two groups. Group 1 (32 women) received magnesium citrate with vitamin B2 for 2 months. Group 2 (33 women) received only vitamin B2 for 2 months, and when that was ineffective, magnesium citrate was added.

## What they found

Group 1 had significant decreases in the overall number of PMS symptoms. When both groups received magnesium citrate (Group 1 from the start, Group 2 after 2 months), specific symptoms significantly decreased: anxiety, depression, resentment, tearfulness, and headache. Other PMS symptoms decreased but not significantly. Blood magnesium levels did not change significantly.

## What it means for you

Magnesium with B2 may help several emotional and stress-related PMS symptoms. The study is small with no true control group, since the second group eventually received the same treatment. We cannot tell if magnesium itself works or if it's the combination with B2.

32

women receiving magnesium citrate and vitamin B2

33

women receiving vitamin B2 only initially

2 months

treatment duration

## About the study

Original title The role of magnesium in the treatment of premenstrual syndrome Authors Lyudmila A. Ozolinya, Озолиня Людмила Анатольевна, Aleksey V. Overko et al. Year 2020 Study design Survey study Participants 65 What was tested Magnesium citrate with vitamin B2 Read the paper [doi.org/10.17816/2313-8726-2020-7-2-102-107](https://doi.org/10.17816/2313-8726-2020-7-2-102-107)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Magnesium](https://niyora.com/research/topics/treatment-magnesium/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

## Related studies

Systematic review, 2025

Do nutritional interventions help with emotional symptoms of PMS?

Systematic review, 2013

Does Vitex (chaste tree) help PMS and PMDD symptoms?

Systematic review, 2009

Which herbs, vitamins and minerals help treat PMS?

Systematic review, 2007

What treatments work for premenstrual syndrome?

Randomised trial, 2003

What treatments work for PMS and PMDD?

Randomised trial, 2003

What complementary and alternative medicines help with women's reproductive health issues?

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗
