---
title: How can gonadotropin-releasing hormone (GnRH) analog drugs be used to treat gynaecological conditions?
description: This review notes that GnRH analog drugs reduce hormone production and are being studied as potential treatments for several gynaecological conditions, though
url: https://niyora.com/research/papers/therapeutic-uses-of-gonadotropin-releasing-hormone-analogs-1987/
---

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- How can gonadotropin-releasing hormone (GnRH) analog drugs be used to treat gynaecological conditions?

Review, 1987

# How can gonadotropin-releasing hormone (GnRH) analog drugs be used to treat gynaecological conditions?

This review notes that GnRH analog drugs reduce hormone production and are being studied as potential treatments for several gynaecological conditions, though evidence is still being gathered.

 Early or limited evidence

Multiple populations from reviewed studies (specific numbers not stated)

## What they did

A literature review of studies investigating GnRH agonistic and antagonistic analog drugs for treating gynaecological conditions by suppressing hormones.

## What they found

GnRH agonists reduce gonadotropin secretion and create a low-hormone state. These drugs are being investigated as potential contraceptives and for treating conditions where lowering reproductive hormones is helpful. Substantial progress has been made in these areas.

## What it means for you

These hormone-suppressing drugs are potentially useful for gynaecological conditions, though more evidence is being gathered. They are not specifically about PMS or PMDD treatment.

1971

Year GnRH was discovered and synthesized

## About the study

Original title Therapeutic uses of gonadotropin-releasing hormone analogs Authors Andreyko JL, Marshall LA, Dumesic DA et al. Journal Obstetrical & gynecological survey Year 1987 Study design Review What was tested GnRH analog drugs (agonists and antagonists) Read the paper [doi.org/10.1097/00006254-198701000-00001](https://doi.org/10.1097/00006254-198701000-00001)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Endometriosis](https://niyora.com/research/topics/comorbidity-endometriosis/)[Work and productivity](https://niyora.com/research/topics/life-area-work/)

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