--- title: Does Kamikihito herbal medicine help PMS and menstrual pain? | Niyora description: Three women with PMS, menstrual pain, and sleep problems improved when treated with Kamikihito, a Japanese herbal medicine. However, this is just three cases url: https://niyora.com/research/papers/three-cases-of-premenstrual-syndrome-and-menstrual-pain-with-the-depression-2014/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Does Kamikihito herbal medicine help PMS and menstrual pain? Study, 2014 # Does Kamikihito herbal medicine help PMS and menstrual pain? Three women with PMS, menstrual pain, and sleep problems improved when treated with Kamikihito, a Japanese herbal medicine. However, this is just three cases without comparison to other treatments, so we cannot say whether the medicine or other factors caused the improvement. Early or limited evidence 3 women with PMS and menstrual pain (ages 26, 38, and 31) ## What they did Reported on three women treated with Kamikihito, a Japanese herbal medicine made from another herbal formula plus two additional herbs. The women had PMS, menstrual pain, fatigue, insomnia, and depression or similar mood symptoms. ## What they found Woman 1, age 26, had premenstrual irritability, breast pain, menstrual pain, fatigue, and insomnia. After treatment, insomnia and fatigue improved, and PMS and menstrual pain improved. Woman 2, age 38, had fatigue, insomnia, and premenstrual irritability. After treatment, fatigue improved and PMS and menstrual pain improved. Woman 3, age 31, had fatigue, insomnia, depression, repeated bladder infections, and PMS. After treatment, PMS and menstrual pain improved and bladder infections stopped. ## What it means for you These three cases suggest Kamikihito might help PMS and menstrual pain, especially in women with fatigue and sleep problems. However, without studying more women or comparing to other treatments, we cannot know whether the medicine worked or if improvement came from other reasons. 3 Case reports 26, 38, 31 Ages of the three women ## About the study Original title Three Cases of Premenstrual Syndrome and Menstrual Pain with the Depression Tendency and Insomnia Successfully Treated with Kamikihito Authors Mayuko Yamazaki, Yoko KIMURA, Hiroshi Satō Journal 日本東洋醫學雜誌 Year 2014 Study design Study What was tested Kamikihito herbal medicine Open access Yes Read the paper [doi.org/10.3937/kampomed.65.273](https://doi.org/10.3937/kampomed.65.273) ## Topics [Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Dysmenorrhea and period pain](https://niyora.com/research/topics/condition-dysmenorrhea/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[Sleep and insomnia](https://niyora.com/research/topics/symptom-sleep/)[Pain and headache](https://niyora.com/research/topics/symptom-pain/) Research tells you what helps on average. Niyora helps on the day it hits. Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor. ## Related studies Survey study, 2025 Do menstrual problems and poor sleep affect mood and thinking in teenage girls? Survey study, 2023 What factors make PMS worse in college students? Survey study, 2019 What lifestyle and sleep habits are linked to PMS in teenage girls? Survey study, 2017 Does painful menstruation affect adolescent girls' mood, emotions, sleep, and thinking? Survey study, 2023 What factors most influence PMS severity in college students? Survey study, 2023 Does connective tissue manipulation help dysmenorrhea pain and other symptoms? Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗