---
title: Do women with PMS have different thyroid hormone levels during their menstrual cycle?
description: Average thyroid hormone levels were the same in women with PMS and control women. Women with PMS showed much greater variation in hormone levels between cycle
url: https://niyora.com/research/papers/thyroid-axis-function-during-the-menstrual-cycle-in-women-with-premenstrual-1995/
---

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- Do women with PMS have different thyroid hormone levels during their menstrual cycle?

Study, 1995

# Do women with PMS have different thyroid hormone levels during their menstrual cycle?

Average thyroid hormone levels were the same in women with PMS and control women. Women with PMS showed much greater variation in hormone levels between cycle phases.

 Early or limited evidence

15 women with PMS and 15 control women

## What they did

Fifteen women with PMS and 15 control women had thyroid hormones measured twice: once during the first half of their cycle and once during the second half. Researchers measured TSH, T3 uptake, T4, and FTI.

## What they found

Average thyroid hormone levels were the same in women with PMS and control women during both cycle phases. Women with PMS showed much greater changes in hormones (TSH, T3 uptake, T4, FTI) between the two phases compared to control women. Reverse T3 was higher during the second half of the cycle than the first half.

## What it means for you

Women with PMS may experience more thyroid instability across their cycle, which could contribute to symptoms. The study was very small with only two hormone measurements per woman, so results may not apply to all women with PMS. It remains unclear whether thyroid changes cause or are associated with PMS.

15

women with PMS

15

control women

4

thyroid hormones measured

## About the study

Original title Thyroid axis function during the menstrual cycle in women with premenstrual syndrome Authors Girdler SS, Pedersen CA, Light KC Journal Psychoneuroendocrinology Year 1995 Study design Study Participants 15 What was tested None Read the paper [doi.org/10.1016/0306-4530(94)00068-9](https://doi.org/10.1016/0306-4530(94)00068-9)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Thyroid disorders](https://niyora.com/research/topics/comorbidity-thyroid/)

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