---
title: Does dienogest help premenstrual mood changes in someone with schizophrenia?
description: One woman with schizophrenia improved in her premenstrual mood symptoms and returned to work. This is one person's experience, so we can't be sure others woul
url: https://niyora.com/research/papers/treatment-of-premenstrual-mood-changes-in-a-patient-with-schizophrenia-using-2018/
---

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- Does dienogest help premenstrual mood changes in someone with schizophrenia?

Case report, 2018

# Does dienogest help premenstrual mood changes in someone with schizophrenia?

One woman with schizophrenia improved in her premenstrual mood symptoms and returned to work. This is one person's experience, so we can't be sure others would benefit.

 Early or limited evidence

One 37-year-old woman with schizophrenia and premenstrual mood changes

## What they did

Doctors treated one 37-year-old woman with schizophrenia who had severe mood changes before her period. She had tried high doses of antidepressants and birth control pills (which caused bad side effects). She was given dienogest, a medication usually used for endometriosis.

## What they found

Her mental health improved. She was able to return to work and had no adverse effects from the medication.

## What it means for you

This is one woman's experience. She also had endometriosis, so we're not sure if dienogest would help others with just the mood symptoms. It may be worth trying for women with schizophrenia and premenstrual mood changes, but more research is needed.

37 years old

age of patient

## About the study

Original title Treatment of premenstrual mood changes in a patient with schizophrenia using dienogest: A case report Authors Kamada Y, Sakamoto A, Kotani S et al. Journal The journal of obstetrics and gynaecology research Year 2018 Study design Case report What was tested Dienogest (a progestin medication) Read the paper [doi.org/10.1111/jog.13578](https://doi.org/10.1111/jog.13578)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Premenstrual dysphoric disorder (PMDD)](https://niyora.com/research/topics/condition-pmdd/)[Premenstrual exacerbation (PME)](https://niyora.com/research/topics/condition-pme/)[Low mood and depression](https://niyora.com/research/topics/symptom-depression-mood/)[SSRIs and antidepressants](https://niyora.com/research/topics/treatment-ssri/)[Oral contraceptives and drospirenone](https://niyora.com/research/topics/treatment-hormonal-contraceptives/)[GnRH agonists and ovarian suppression](https://niyora.com/research/topics/treatment-gnrh/)[Schizophrenia and psychosis](https://niyora.com/research/topics/comorbidity-psychosis/)[Endometriosis](https://niyora.com/research/topics/comorbidity-endometriosis/)

Research tells you what helps on average. Niyora helps on the day it hits.

Calm down, see it another way, and decide what to say, with a PMS and PMDD app built by a doctor.

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