---
title: Does chasteberry help premenstrual syndrome? | Niyora
description: Yes, based on 3 high-quality trials, women taking chasteberry were 2.57 times more likely to experience symptom improvement compared to placebo. However, evid
url: https://niyora.com/research/papers/vitex-agnus-castus-in-premenstrual-syndrome-a-meta-analysis-of-double-blind-2019/
---

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- Does chasteberry help premenstrual syndrome?

Systematic review, 2019

# Does chasteberry help premenstrual syndrome?

Yes, based on 3 high-quality trials, women taking chasteberry were 2.57 times more likely to experience symptom improvement compared to placebo. However, evidence is limited because only 3 rigorous studies met quality criteria.

 Moderate study design

520 women with premenstrual syndrome in 3 high-quality randomized controlled trials

## What they did

Meta-analysis of randomized, double-blind, placebo-controlled trials of chasteberry (Vitex agnus-castus) preparations. From 21 trials identified, 3 met high-quality criteria, involving 520 women total.

## What they found

Women taking chasteberry were 2.57 times more likely to have remission of PMS symptoms compared to placebo (95% confidence interval 1.52 to 4.35). Only 3 trials met strict quality criteria for proper reporting and herbal product characterization.

## What it means for you

Chasteberry appears effective for PMS based on good-quality evidence. However, evidence is limited to only 3 rigorous trials. Most published studies had poor reporting. More trials following strict reporting standards are needed.

520

women in high-quality trials

3

rigorous trials of 21 identified

2.57

times more likely to improve vs placebo

## About the study

Original title Vitex agnus-castus in premenstrual syndrome: A meta-analysis of double-blind randomised controlled trials Authors Csupor D, Lantos T, Hegyi P et al. Journal Complementary therapies in medicine Year 2019 Study design Systematic review What was tested Chasteberry (Vitex agnus-castus) extracts Ze 440 and BNO 1095 versus placebo Read the paper [doi.org/10.1016/j.ctim.2019.08.024](https://doi.org/10.1016/j.ctim.2019.08.024)

## Topics

[Premenstrual syndrome (PMS)](https://niyora.com/research/topics/condition-pms/)[Vitex agnus-castus (chasteberry)](https://niyora.com/research/topics/treatment-vitex/)[Other herbal medicine](https://niyora.com/research/topics/treatment-herbal-other/)

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