--- title: ADHD: 34 studies, explained | Niyora description: 34 studies on adhd and PMS or PMDD, each summarised in plain English: what was tested, who took part, what they found and what it means. url: https://niyora.com/research/topics/comorbidity-adhd/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - ADHD # ADHD: what the research says 34 studies on adhd in PMS and PMDD, each explained in plain English. 2 of them use the strongest designs: randomised trials and systematic reviews. Survey study 16 Study 5 Cohort study 3 Review 3 Interview study 2 Case-control study 1 Cohort study, 2023 Are PMS symptoms linked to genetic factors for psychiatric disorders? Yes. Women with PMS were more likely to have genetic factors for depression, bipolar disorder, ADHD, schizophrenia, and autism spectrum disorder. This was a large, well-designed study, so we can be confident in these findings. Cohort study, 2023 Is PMDD a valid medical diagnosis? Yes. PMDD is recognized by the World Health Organization and American Psychiatric Association as a distinct medical diagnosis. Evidence suggests it has real neurobiological basis, though more biological research is still needed to fully understand it. Survey study, 2026 Are menstrual characteristics linked to depression and anxiety in teenage girls? Yes. Girls with earlier periods, irregular cycles, long cycles, severe period pain, and worse premenstrual symptoms have higher depression and anxiety scores, and these links get stronger as girls get older. Survey study, 2026 Do people with ADHD traits have higher rates of PMDD than others? Yes, people with ADHD traits had significantly higher risk of PMDD. People with autism traits did not show a higher risk of PMDD. Survey study, 2026 Are PMDD and ADHD linked in women with bipolar disorder? In women with bipolar disorder, 44.2% have PMDD, and those with PMDD also have higher ADHD symptom scores. Genetic risk for ADHD was linked to both PMDD severity and ADHD symptoms. Survey study, 2026 Do women with ADHD and autism have more premenstrual problems than women without these conditions? Yes, women with ADHD and autism have significantly more premenstrual problems than women without these conditions, with equal severity in both groups. Premenstrual symptoms are linked to traits like inattention and social difficulties. Study, 2025 Do ADHD symptoms get worse in the week before your period? Yes. Women with ADHD had more symptoms, worse sleep, and higher stress in the late luteal phase (the week or so before their period), and they took more medication during this time. Review, 2025 How does the menstrual cycle affect ADHD symptoms and concentration? Women with ADHD experience worse attention and executive function during the mid-luteal and premenstrual phases, whereas women without ADHD show improved attention during these phases. Research is still limited. Case-control study, 2024 Do women with PMDD have more attention and memory problems than other women? Yes, women with PMDD show greater increases in memory and attention problems as they progress through their menstrual cycle toward their period. Women with PMDD are also more likely to have ADHD. Lab study, 2017 Do women with PMS process emotions differently? Yes. Women with PMS are slower to respond to emotional pictures and faces during their premenstrual phase, compared to women without PMS. Survey study, 2011 How common is PMS in working women, and do they know about it? Between 38% and 74% of working women have PMS depending on which diagnostic criteria are used. Most women did not know what PMS was and rarely saw doctors about it. Survey study, 2026 Do women with ADHD have worse menstrual, pregnancy, and menopause symptoms? Yes, in this large survey women with ADHD reported significantly more menstrual irregularity, worse premenstrual symptoms, higher postpartum depression, and more severe menopausal symptoms than women without ADHD. Survey study, 2026 Do teen girls with ADHD have more suicidal thoughts when angry before their period? Teen girls with ADHD are more likely to have PMDD and premenstrual anger. However, overall depression appears to be the main driver of suicide risk, not premenstrual anger alone. Survey study, 2026 Does ADHD change across the menstrual cycle in women taking stimulants? Yes, clearly. ADHD symptoms were most severe during menstruation and much milder in the mid-follicular phase. This difference was linked to mood changes. Interview study, 2026 How do hormonal fluctuations during the menstrual cycle affect women with ADHD? Women with ADHD reported feeling energetic and productive around ovulation, but struggling with low energy and difficulty managing tasks during the premenstrual week. Healthcare providers often didn't understand this connection. Survey study, 2026 What factors affect how severe PMS is in women with PCOS? Women with PCOS commonly have severe PMS. Smoking, lower education, and not being treated for anemia increase severity, while regular periods decrease it. Review, 2026 What causes PMDD? PMDD happens when the brain is too sensitive to hormonal changes during the menstrual cycle. Many brain systems are involved, but most of the mechanisms still need direct testing. Systematic review, 2026 What do we know about PMDD in autistic people and those with ADHD? Very little research exists on PMDD specifically in autistic people and those with ADHD. Early evidence suggests they may experience more severe symptoms and face barriers to diagnosis, but we cannot yet say for certain. Study, 2026 Could early stress or past trauma make PMDD symptoms worse later in the cycle? This research offers a possible explanation for why PMDD symptoms vary so much, and why related conditions can worsen before a period. It is only a theory, not tested on patients, so we don't yet know if it is true. Review, 2026 Can brain imaging help explain how hormones affect mood in PMDD? A review suggests that advanced PET brain imaging could reveal how neurotransmitters like serotonin and GABA interact with hormonal changes to cause PMDD symptoms. The approach is promising but not yet proven. Survey study, 2025 Are girls with ADHD or autism more likely to have severe PMS or PMDD? Yes, girls with ADHD were 2.43 times more likely to have moderate to severe PMS, and girls with both autism and ADHD were 3.27 times more likely. Girls with only autism did not show this link. Study, 2025 Does taking more ADHD medication during the premenstrual week help women with ADHD? Yes. All 9 women with ADHD who took a higher medication dose during the premenstrual week experienced better focus, mood, and energy during those weeks. Survey study, 2025 Are women with ADHD more likely to have PMDD? Yes. Women with ADHD had PMDD at rates of 31.4% to 41.1%, compared to 9.8% without ADHD. We cannot be completely certain because this study relied on self-reported diagnoses. Survey study, 2025 How do hormonal changes affect ADHD symptoms in women? Hormonal changes significantly impact women with ADHD. Symptoms may get worse during certain parts of the menstrual cycle and after childbirth, often with mood and sleep problems. Interview study, 2024 Do women with ADHD benefit from a group focused on the menstrual cycle? Women with ADHD who attended a group program focused on the menstrual cycle said it was helpful and made them more aware of their symptoms. We do not know if ADHD symptoms actually improved. Survey study, 2024 How does the menstrual cycle affect ADHD symptoms in women? This paper proposes that estrogen drops during the cycle may worsen ADHD symptoms, but this theory is untested and so we cannot yet know if it is true. Non-randomised trial, 2022 Can a simple taste test identify women with ADHD and severe PMS? A simple taste test showed women with both ADHD and severe PMS (PMDD) did not respond to lidocaine as expected. This might point to a physical difference in how their nerve cells work. Survey study, 2022 Do autistic women experience more PMDD and worse menopausal symptoms than non-autistic women? Autistic women did not have more PMDD than non-autistic women (14.3% vs 9.5%), but they reported worse menopausal symptoms linked to depression. Survey study, 2021 Are women with ADHD more likely to experience PMDD and postpartum depression? Yes, very much so. Women with ADHD have significantly higher rates of PMDD and postpartum depression compared to the general population. Survey study, 2017 What is the impact of having both bipolar disorder and premenstrual dysphoric disorder? Women with both conditions experience significantly worse bipolar illness: earlier onset, more rapid cycling, more mood episodes, and higher rates of anxiety disorders and other conditions. They also experience more severe symptoms during pregnancy and while taking oral contraceptives. Study, 2017 Do women with moderate to severe PMS have problems with attention and memory? Yes. Women with moderate to severe PMS made more mistakes and had lower accuracy on attention and memory tests even though tests were done when they didn't have symptoms. Study, 2012 Does mugwort help with premenstrual syndrome? Mugwort is used traditionally for PMS and contains a compound that may work through serotonin. However, there is no clinical research evidence presented here, only historical uses. Cohort study, 2010 How do anxiety disorders differ across different life stages? The provided summary focuses on anxiety in children and risk factors. The section about women and hormones is cut off in the provided text, so no conclusion about menstrual-related anxiety can be drawn. Case report, 1995 Can sleep terrors and sleepwalking happen only before your period? Yes. Two cases showed sleep terrors and dangerous sleepwalking that happened exclusively before menstruation. Self-hypnosis helped both, and one also took a low dose of clonazepam. Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗