--- title: Bloating, breast tenderness and physical symptoms: 330 studies, explai description: 330 studies on bloating, breast tenderness and physical symptoms and PMS or PMDD, each summarised in plain English: what was tested, who took part, what they url: https://niyora.com/research/topics/symptom-physical-symptoms/ --- - [Niyora](https://niyora.com/) - [Research](https://niyora.com/research/) - [Library](https://niyora.com/research/library/) - Bloating, breast tenderness and physical symptoms # Bloating, breast tenderness and physical symptoms: what the research says 330 studies on bloating, breast tenderness and physical symptoms in PMS and PMDD, each explained in plain English. 30 of them use the strongest designs: randomised trials and systematic reviews. Survey study 143 Randomised trial 71 Study 30 Cohort study 22 Review 17 Non-randomised trial 16 Systematic review, 2026 Does vitamin D supplementation help PMS symptoms? Vitamin D reduced overall PMS severity and particularly helped with physical symptoms and depression, but the certainty of this evidence is very low. We cannot be confident in these findings yet and more high-quality research is needed. Systematic review, 2024 Does yoga help PMS symptoms? Yes, yoga helps reduce at least some physical and psychological PMS symptoms, though we need more research on which symptoms it helps most. Randomised trial, 2024 Does estetrol/drospirenone birth control improve PMS symptoms? Yes. Women who started this birth control experienced significant improvements in pain, bloating, and negative mood symptoms. Women already on other birth control saw minimal improvements. Systematic review, 2023 Does body composition affect premenstrual syndrome symptoms? Yes. Higher body weight and more central fat around the belly and hips are linked to more PMS symptoms, more severe symptoms, and higher risk of depression and anxiety in women with PMS. Randomised trial, 2023 Does zinc supplementation reduce PMS symptoms in women? Yes. Daily zinc supplementation for 24 weeks significantly reduced multiple PMS symptoms including anger, anxiety, depressed mood, and physical symptoms like breast tenderness and bloating compared to placebo. Systematic review, 2021 Does damask rose help reduce menstrual pain, headache, fatigue, anxiety, and bloating? Damask rose significantly reduced menstrual-related headache, fatigue, and bloating, but did not clearly reduce menstrual pain or anxiety. More research on pain and anxiety is needed. Randomised trial, 2020 What is the best dose of Vitex for treating PMS? A dose of 20 mg daily was most effective for reducing PMS symptoms. Higher dose (30 mg) was no better, and lower dose (8 mg) was less effective. Systematic review, 2020 Does Vitex agnus-castus help cyclic breast pain? Vitex appears moderately effective for reducing cyclic breast pain compared to placebo, works as well as some medications, and is safe with minimal side effects. Randomised trial, 2014 Does the combination of sumatriptan and naproxen sodium reduce menstrual symptoms and migraine? Yes. The combination was better than placebo for tiredness, irritability, bloating, abdominal pain, and back pain, as well as migraine. However, women with severe period pain responded less well to migraine treatment. Systematic review, 2013 Does Vitex (chaste tree) help PMS and PMDD symptoms? Most studies found Vitex better than placebo for PMS. For PMDD, results were mixed: one study showed it equal to fluoxetine, while another found fluoxetine more effective. Side effects were mild. Randomised trial, 2012 Does Vitex agnus castus work for PMS, and what dose is best? Yes, Vitex at 20 mg daily significantly reduced PMS symptoms compared to placebo. A 30 mg dose did not work better, making 20 mg the optimal dose. Systematic review, 2012 What medications work best for PMDD? The abstract does not include findings or results, so no conclusion can be drawn from it. Survey study, 2011 What premenstrual symptoms do women experience around the world and how much do they affect daily life? The most common symptoms are abdominal bloating, cramps, irritability, breast tenderness, and muscle or back pain. Physical and mental symptoms have similar effects on daily activities. Randomised trial, 2011 Does a birth control pill reduce negative emotions, food cravings, and water retention in women with PMDD? Yes, the pill significantly reduced all three symptom clusters compared to placebo in all three treatment cycles. The greatest improvements happened in the first cycle. Randomised trial, 2010 Does Vitex agnus castus reduce moderate-to-severe PMS in Chinese women? Yes, Vitex extract significantly reduced PMS symptoms by the 3rd cycle, with 60 percent or greater symptom reduction in the treatment group compared to placebo, especially for mood and water retention. Randomised trial, 2009 Does Yasmin birth control reduce PMS symptoms better than another pill? Yes. Yasmin reduced water retention, improved breast tenderness, and improved skin problems more than desogestrel pill. Both prevented pregnancy well. Review, 2009 What causes PMDD and what are the treatment options? PMDD affects an estimated 5-8% of women and causes severe mood and physical symptoms. The cause involves individual sensitivity to hormonal changes. Treatments include serotonin antidepressants, medications that stop ovulation, and certain newer birth control pills. Randomised trial, 2008 Does drospirenone with ethinyl estradiol birth control help PMDD? This birth control formulation is the only hormone-based option with large randomized controlled trials proving it works for PMDD and has FDA approval for this use. Randomised trial, 2006 What herbs and dietary supplements have evidence for treating premenstrual syndrome? A review of research found that calcium, vitamin B6, and chasteberry have the strongest evidence from clinical trials for treating premenstrual syndrome. Randomised trial, 2006 Does toremifene reduce premenstrual breast pain? Yes. Toremifene reduced pain significantly more than placebo, with a 64% reduction in pain compared to 26% with placebo. Randomised trial, 2004 Which low-dose birth control pill has better cycle control and fewer side effects? Both pills equally reduced period pain and PMS. One type (with desogestrel) had more stable bleeding patterns and less acne than the other (with levonorgestrel). Both were well tolerated overall. Randomised trial, 2003 What treatments work for PMS and PMDD? Several treatments work. Non-drug options include cognitive behavioral therapy, exercise, and supplements like calcium and magnesium. Many studies support SSRIs (taken daily or only before menstruation). Hormonal treatments that stop ovulation also help. Randomised trial, 2002 Does daily fluoxetine help PMDD? Yes. Fluoxetine 20 mg improved mood and physical symptoms compared to placebo. The 10 mg dose showed some benefits but was not as strong. Both were well tolerated. Randomised trial, 2002 Does taking fluoxetine only before your period help PMDD? Yes, at a dose of 20 mg per day. This dose reduced mood symptoms and physical symptoms like breast tenderness and bloating, starting 14 days before the period through the first day of bleeding. Randomised trial, 2001 Does fluoxetine help the physical symptoms of PMDD? Fluoxetine taken daily was significantly better than placebo at improving physical symptoms like breast tenderness, bloating, and headache. Both 20 mg and 60 mg doses worked similarly. Randomised trial, 1997 Does tamoxifen or danazol help severe cyclical breast pain? Yes. Both drugs reduced pain more than placebo during treatment, but tamoxifen was more effective and longer-lasting, with 53% still symptom-free 12 months after stopping. Randomised trial, 1995 Does spironolactone help PMS symptoms? Yes. Spironolactone significantly reduced mood symptoms like irritability and depression, and physical symptoms like breast tenderness and bloating, compared to placebo. Survey study, 1994 How many different ways do researchers measure PMS in clinical trials? Researchers use many different measurement tools across studies. 65 different questionnaires were found in 350 trials of PMS drugs, making it hard to compare whether treatments actually work. Randomised trial, 1993 Does endometrial resection work as well as hysterectomy for heavy periods? Endometrial resection was almost as satisfying as hysterectomy, with 84 out of 99 women satisfied versus 89 out of 95 with hysterectomy. However, hysterectomy was better for reducing premenstrual symptoms like painful periods, bloating, and breast tenderness. Randomised trial, 1983 Is bromocriptine effective for premenstrual syndrome? No substantial evidence that bromocriptine works for premenstrual syndrome overall. It may help breast pain if the dose is at least 5 mg daily. Survey study, 2026 Does light exposure, exercise, and meal timing affect PMS severity? Yes, for some women. Morning-type women with more evening screen time had worse mood symptoms. Evening-type women with less daytime light had worse mood and water retention. Meal timing did not significantly affect PMS. Study, 2026 What are premenstrual syndrome and premenstrual dysphoric disorder? Between 5% and 8% of women have moderate-to-severe symptoms that cause significant problems with work, relationships, and daily life. These are called PMS or PMDD. PMDD is the most severe form. Cohort study, 2025 When during the menstrual cycle do breast tenderness and swelling occur? Breast tenderness and swelling happen mainly in the late luteal phase (after ovulation). They were higher in cycles with normal ovulation compared to cycles with ovulation problems. Systematic review, 2025 Do diet changes or supplements help PMS symptoms? Most studies showed diet changes and supplements reduced PMS symptoms, but many studies had quality concerns so we cannot be certain how much they truly help. Cohort study, 2025 Do estrogen and progesterone each trigger PMDD symptoms differently? Yes, likely. Both hormones triggered mood symptoms in women with PMDD when reintroduced after suppression, but progesterone appeared more closely linked to irritability and mood swings than estrogen. Case-control study, 2025 Do women with eating disorders experience more menstrual distress, and does birth control help? Yes, women with eating disorders reported significantly more menstrual distress than healthy women across all symptoms measured. Birth control reduced distress only in those with milder eating disorder symptoms, not in those with more severe symptoms. Survey study, 2025 How common is PMDD in Brazilian women and what are the most frequent symptoms? PMDD affects 3.57% of Brazilian women. Emotional symptoms like anxiety and irritability are much more common than physical symptoms like weight gain. Survey study, 2025 Are premenstrual symptoms linked to depression in teenage girls? Yes. Girls with premenstrual symptoms were about 1.7 times more likely to have depressive symptoms than girls without PMS. Study, 2024 Does a combination of evening primrose oil, tocotrienol, and vitamin B6 reduce premenstrual symptoms? Yes. In women with PMS taking this combination for 3 months, premenstrual symptoms improved significantly. The overall PMS score dropped by 61.03%, menstrual pain dropped by 75.20%, and breast tenderness dropped by 82.54%. Randomised trial, 2024 Do hormonal changes in obese women cause worse PMS, and can medications help? Yes, obese women with PMS had significantly higher stress hormone levels than healthy women, and a combination treatment of medications, diet, and exercise significantly reduced these hormones and PMS symptoms. Cohort study, 2024 Does Vitex supplement improve menstrual cycle problems and quality of life? Yes, after 3 months of treatment, most women showed improvement in irregular periods, pain, and breast tenderness. Quality of life improved for all participants. Randomised trial, 2023 Does gamma-tocopherol (a form of vitamin E) reduce premenstrual syndrome symptoms? Yes. Gamma-tocopherol significantly reduced fatigue and anger, and also reduced leg swelling. Because this was a well-designed controlled trial where each woman tried both treatments, we can be fairly confident about these effects. Cohort study, 2023 Does recreational physical exercise reduce premenstrual symptoms in teenage girls? Possibly. Girls who exercised 3 or more times per week had lower depression. However, older age and higher weight were linked to worse symptoms. Survey study, 2022 What diet, stress, and lifestyle factors are linked to PMS symptoms? High coffee intake, sugar, stress, smoking, and low physical activity were all linked to worse PMS symptoms, with stress showing the strongest association. These are associations only, not proven causes. Survey study, 2022 What factors are linked to PMS in teenage girls? Most teenage girls have some PMS. Backache and breast tenderness are common physical symptoms. Irritability, anxiety, and mood swings are common emotional symptoms. Eating sweets, education level, and family circumstances are linked to PMS, but body weight is not. Cohort study, 2022 Does living in greener areas reduce PMS symptoms? Yes, women living in greener areas had lower rates of several PMS symptoms including anxiety, depression, sleep problems, and breast tenderness. The effect was modest but consistent. Survey study, 2022 How common are premenstrual symptoms, and do they change with age? Very common. Food cravings affect 85%, mood swings 64%, and fatigue 57%. Several symptoms got worse with age, but mood symptoms stayed the same across all age groups. Case-control study, 2021 What causes adult female acne and makes it worse? Family history of acne increases your risk of adult female acne, but diet, weight, and premenstrual flare do not. Severity is not related to any of these factors. Randomised trial, 2021 Does Lactobacillus gasseri CP2305 help premenstrual symptoms? It may help mood and anxiety symptoms before your period, but it does not help water retention symptoms like breast swelling. Randomised trial, 2021 Does hypnotherapy reduce pain and emotional distress in women with PMDD? Yes. Hypnotherapy focusing on cognitive flexibility and ego strength reduced pain and emotional distress much more than no treatment. Survey study, 2021 What factors affect premenstrual syndrome in teenage girls? Multiple factors affect PMS. These include how active you are physically, what you eat (especially coffee), stress, and feelings of insecurity. Randomised trial, 2020 Does saffron reduce PMS symptoms as well as fluoxetine? Yes, saffron reduced PMS symptoms similarly to fluoxetine and may even be better for breast and abdominal pain with potentially fewer side effects. Randomised trial, 2020 Does progesterone therapy help premenstrual syndrome in women with PCOS? Yes, progesterone significantly reduced multiple emotional PMS symptoms in women with PCOS, including depression, anxiety, and mood swings. Survey study, 2019 Does low vitamin D make premenstrual symptoms worse? Yes, for some symptoms. Women with inadequate vitamin D were about 1.5 to 2 times more likely to have moderate to severe cramps, fatigue, anxiety, and confusion before their period. Low vitamin D did not increase the risk of other symptoms like bloating or headaches. Randomised trial, 2019 Does chasteberry (Vitex agnus-castus) help premenstrual breast pain and related symptoms? Yes, according to multiple placebo-controlled studies reviewed here, chasteberry extracts reduced premenstrual breast pain and other premenstrual symptoms, likely by lowering prolactin, and side effects were mild and infrequent. Cohort study, 2018 Can the premenstrual feelings women get tell us whether ovulation actually occurred? No. While 89% of women reported premenstrual feelings that helped them predict their period, these symptoms did not reliably show whether ovulation actually happened. Randomised trial, 2018 Does progressive muscular relaxation help premenstrual syndrome symptoms? Progressive muscular relaxation helped reduce leg cramps and irritability. However, the control group also improved without treatment, so it is unclear how much the relaxation itself helped. Randomised trial, 2018 Does swimming reduce premenstrual syndrome symptoms? Yes. Swimming significantly reduced anxiety, depression, cramps, headaches, and most other PMS symptoms, but it did not help irritability or food cravings. Randomised trial, 2017 Does a dermocosmetic cream help with premenstrual acne flare-ups? Yes. A dermocosmetic containing lipohydroxyacid, nicotinamide, and piroctone-olamine reduced inflammatory acne lesions during the premenstrual phase compared to placebo. Systematic review, 2017 Do estrogen patches or gels help control PMS symptoms? Estrogen patches and gels work by stopping ovulation and the hormone changes that cause PMS. However, the abstract does not provide results from the trials reviewed, so effectiveness cannot be assessed. Cohort study, 2017 How common is PMS in high school students, and what symptoms and problems does it cause? About 3 in 10 of the Thai high school students in this study had PMS, and the most common symptoms were angry outbursts and breast tenderness. PMS was linked to problems with concentration and schoolwork, but not with how they got along with others. Survey study, 2017 Do women using hormonal birth control have fewer menstrual symptoms? Most women have menstrual symptoms regardless of birth control use. Women not using hormonal contraception report slightly more symptoms on average (5.9 versus 5.3 symptoms). Survey study, 2016 Do hormonal contraceptives reduce PMS symptoms? Hormonal contraceptives are linked to lower risk of some PMS symptoms, including cramps, fatigue, and depression, but not others like mood swings and bloating. Survey study, 2016 Does yoga or calcium help reduce PMS symptoms in medical students? Both yoga and calcium reduced the number and severity of PMS symptoms over 3 months, while the control group had no improvement. This is a small study, so larger studies are needed to confirm the benefits. Randomised trial, 2016 Does cognitive-behavioral therapy improve quality of life in women with premenstrual syndrome? Yes. Group cognitive-behavioral therapy significantly improved quality of life in women with PMS, and the benefits lasted for 2 months after treatment ended. Cohort study, 2016 Is inflammation linked to premenstrual symptoms? Yes, high inflammation (measured as hs-CRP above 3 mg/L) was associated with mood problems, cramping, bloating, and breast pain in this study. Cross-sectional design means we cannot prove inflammation causes these symptoms. Cohort study, 2015 Do symptoms of acute intermittent porphyria change during the menstrual cycle? Yes. 30 of 32 women with this rare disease showed symptom changes across their menstrual cycle. Breast tenderness and abdominal swelling showed the strongest changes. Study, 2015 Does treating the uterus with injections and freezing help severe PMS and PMDD? Women in this study who received cervical injections and freezing showed very large improvements in their PMS and PMDD symptoms. Randomised trial, 2014 Is chamomile as effective as mefenamic acid for breast pain associated with PMS? Yes. Chamomile appeared to be similarly effective as mefenamic acid (a standard pain medicine) at reducing the intensity of breast pain associated with PMS. Survey study, 2013 Are menstrual symptoms common in middle-aged women and do they relate to hot flushes? Cramping is common (54%) but mood symptoms are less frequent (8-9%). Cramping and back pain were associated with hot flushes, suggesting hormonal changes may affect both. Randomised trial, 2013 Does progesterone reduce PMS symptoms in women with polycystic ovary syndrome? Yes. Women with PCOS and PMS who took progesterone had significant reductions in depression, anxiety, mood swings, bloating, and several other PMS symptoms compared to placebo. Survey study, 2012 How common are PMS and severe PMS in Chinese women, and what are the typical symptoms? In Chinese women, PMS affects 21.1% and severe PMS affects 2.1%. The most common symptoms are irritability, breast tenderness, depression, abdominal bloating, and angry outbursts. Survey study, 2011 How do premenstrual symptoms change as women age, and what factors influence them? Premenstrual symptoms follow different patterns as women age: some stay the same, some decrease, some peak around age 35, and others peak around age 40-44. Smoking is linked to more symptoms, and having more pregnancies is linked to fewer symptoms. Survey study, 2011 How common is PMS in working women, and do they know about it? Between 38% and 74% of working women have PMS depending on which diagnostic criteria are used. Most women did not know what PMS was and rarely saw doctors about it. Randomised trial, 2010 Which works better for premenstrual breast pain, cabergoline or bromocriptine? Both drugs reduced breast pain equally well, with about two-thirds of women in each group responding. Cabergoline caused far fewer side effects. Survey study, 2010 Do women with premenstrual asthma have more premenstrual symptoms overall? Yes. Women whose asthma worsens before their period had greater increases in most premenstrual symptoms, especially belly and breast tension, compared to women without this pattern. Randomised trial, 2010 Does toremifene reduce breast pain by changing hormone levels? Toremifene helped breast pain, but it didn't change the hormone levels tested, so how it works remains unclear. Study, 2009 Does evening primrose oil help treat PMS? No. Based on current evidence, evening primrose oil is likely ineffective for PMS. Most studies to date have had major methodologic flaws. Survey study, 2009 What are the most common premenstrual symptoms and how severe are they? The most common symptoms are bloating, cramps, breast tenderness, irritability, and mood swings. Symptoms varied widely: 40.8% of women had mild symptoms, 28.7% had moderate mental symptoms, 21.9% had moderate physical symptoms, and 8.6% had severe symptoms. Survey study, 2009 Are women satisfied with drospirenone birth control? Yes, about 95% were satisfied with this birth control and 83% would recommend it to a friend. Many reported improvements in skin and weight. Study, 2008 Is YAZ birth control safe and does it help PMDD? YAZ is a birth control pill approved to prevent pregnancy, treat PMDD, and treat moderate acne. Large studies found it is safe with no increased risk of serious blood complications compared to other birth control pills. Non-randomised trial, 2007 Does a birth control pill with drospirenone reduce water retention symptoms? Yes. Women taking this pill had significant reduction in water retention symptoms during the premenstrual and menstrual phases, with no weight gain. Survey study, 2007 Are diet and lifestyle factors associated with premenstrual symptoms? Most dietary factors were not related to PMS. Smoking increased symptoms, and alcohol was associated with fewer mood and headache symptoms. Randomised trial, 2007 Does drospirenone/ethinylestradiol birth control help PMDD symptoms? Yes. This specific birth control pill significantly improved PMDD symptoms over three cycles and improved acne over six cycles while providing 99% contraceptive protection over one year. Cohort study, 2007 Does the combined oral contraceptive pill improve quality of life for women with PMS? Yes, the pill improved quality of life for women taking it for menstrual pain and PMS symptoms. Women taking it only for contraception had mixed results. Randomised trial, 2006 Does aspirin or vitamins help with cyclic breast pain before your period? No, neither aspirin nor a vitamin combination worked better than placebo. The placebo group actually improved the most. Randomised trial, 2005 Which birth control pill reduces PMS symptoms better: drospirenone or levonorgestrel? Drospirenone-containing pills reduced PMS symptoms more effectively than levonorgestrel pills after six cycles, especially mood symptoms and water retention. Randomised trial, 2005 Do soy isoflavones reduce premenstrual syndrome symptoms? Soy isoflavones reduced specific PMS symptoms like headache, breast tenderness, cramps, and swelling better than placebo. However, overall PMS improved on both soy and placebo, showing the placebo effect is strong. The true benefit of soy beyond placebo is modest. Randomised trial, 2003 Does chaste tree help premenstrual symptoms? Chaste tree extract has been shown in controlled studies to help breast tenderness before the period and may help other premenstrual symptoms. It works by reducing prolactin, a hormone linked to breast tissue. Study, 2003 Do breast tenderness and hot flushes follow a pattern during the month? Breast tenderness and night sweats clearly increased in the days before a period in most cycles. Daytime hot flushes did not show a clear pattern related to cycle timing overall, except in cycles when ovulation occurred. Non-randomised trial, 2002 Does birth control containing drospirenone reduce premenstrual symptoms? In this study, birth control containing drospirenone (3 mg) reduced mood-related symptoms and water retention by the sixth cycle. Without a control group, we cannot be certain these improvements were caused by the pill rather than placebo effect. Randomised trial, 2002 What treatments work best for cyclical breast pain? Initial treatments like reassurance, proper bra fit, reducing caffeine, and primrose oil should be tried first. Medications like danazol work but often cause side effects. Randomised trial, 2002 Does the birth control pill Yasmin help women with PMDD? Yes, women taking Yasmin had greater reduction in premenstrual symptoms compared to placebo, with statistically significant improvements in appetite, acne, and food craving. Review, 2002 Does the new oral contraceptive Yasmin improve premenstrual symptoms and well-being? Yes. Women with premenstrual symptoms who took Yasmin showed improved well-being scores and fewer physical symptoms compared to before starting the medication. Cohort study, 2002 How much do genes versus environment contribute to PMS symptoms? Genes accounted for 44% of PMS symptom differences. Genes for PMS overlap with genes for neuroticism and depression but 39% of PMS genetic variance is independent of these traits. Survey study, 2001 What behaviors and factors are linked to breast pain during the menstrual cycle? Smoking, caffeine consumption, and stress are each associated with more breast pain. Birth control pills are associated with less breast pain and PMS. Non-randomised trial, 2001 Does a new birth control pill reduce PMS symptoms? Yes. In 322 women, after 6 cycles of this pill, negative mood and water retention during the premenstrual phase dropped significantly. However, this study had no control group, so we cannot be certain the pill itself caused the improvement rather than a placebo effect. Randomised trial, 2001 Does lisuride maleate help premenstrual breast pain? Yes. Lisuride maleate significantly reduced premenstrual breast pain compared to placebo, with no significant side effects reported. Randomised trial, 2000 Does a nicotine patch help reduce smoking cravings and premenstrual symptoms? Yes, a nicotine patch reduced smoking cravings and some premenstrual symptoms including pain and water retention, with the strongest effects during the late luteal phase. Randomised trial, 1999 Does danazol given only during the luteal phase help PMS and breast pain? Danazol was highly effective for premenstrual breast pain but not for general PMS symptoms, with minimal side effects. Survey study, 1999 How much do premenstrual symptoms affect women's work and daily life? Premenstrual symptoms significantly affect daily life and work. About 80% of women report irritability, fatigue, and bloating. Over half of working women report some impact on work. Nearly three-quarters have never sought treatment, even though effective medicines exist. Randomised trial, 1999 Does a low-dose GnRH agonist relieve premenstrual symptoms while keeping regular periods? Low-dose GnRH agonist significantly relieved irritability and depression, and improved physical symptoms like swelling and headache. However, it stopped ovulation in 56% of women, making it unsuitable for long-term use if you want regular cycles. Randomised trial, 1998 Does tamoxifen treat premenstrual breast pain? Yes, 90% of women taking tamoxifen had complete resolution of breast pain. However, 86% of the placebo group also improved, suggesting a strong placebo effect. Survey study, 1998 How common is PMS and what treatments do women use? 41% of US women said they had PMS, and an additional 17% experienced PMS symptoms without labeling them as PMS. Of those with symptoms, 42% used medication, mostly over-the-counter drugs; most who tried complementary therapy like exercise found it helpful. Randomised trial, 1998 Does 200 mg magnesium daily help premenstrual symptoms? Yes, but only for fluid retention symptoms like bloating and breast swelling, and only during the second month of treatment. Study, 1998 What are the best treatments for PMS? Treatment depends on your specific symptoms. For some women, exercise and diet help. Others need medicines like hormones or psychiatric drugs. Randomised trial, 1998 Does Vitex agnus castus help cyclical breast pain? Yes. The extract reduced breast pain faster than placebo and was well tolerated. Survey study, 1997 How common is breast pain before your period and does it affect daily life? Very common. 69% of women get premenstrual breast discomfort and 11% have moderate-to-severe pain. It affects sexual activity in 48% of women. Randomised trial, 1995 Is paroxetine better than other antidepressants for treating severe PMS? Yes. Paroxetine reduced symptoms much more than placebo. It also worked better than maprotiline for most symptoms. Randomised trial, 1994 Does stopping ovulation help severe premenstrual tension? Yes, a drug that stops ovulation (goserelin) reduced breast discomfort and swelling significantly. It also reduced mood swings, though the effect on mood was weaker and had a strong placebo component. Randomised trial, 1992 Does a triphasic birth control pill help premenstrual symptoms? It reduced breast pain and bloating but did not help mood symptoms. Women also experienced decreased sexual interest as a side effect. Randomised trial, 1992 Does bromocriptine help premenstrual syndrome? Bromocriptine helped significantly with physical symptoms like abdominal tension, water retention, weight gain, and breast tenderness. It was less clear whether it helped with mood symptoms like depression and irritability. Randomised trial, 1991 Does calcium help PMS symptoms? Yes. Calcium reduced negative mood, water retention, and pain during the week before your period, and reduced pain during your period. Survey study, 1990 Does the type of contraceptive pill affect premenstrual symptoms? Women taking a monophasic pill (steady hormone levels) had less breast tenderness before their period than women on other pills or no hormonal contraceptives. Other premenstrual symptoms were similar across all groups. Survey study, 1990 What do we know about what causes PMS and how common it is? A literature review found PMS affects 30 to 40% of women, especially those who work outside the home, have had multiple children, or use alcohol. Many theories about causes exist, but none are proven. Randomised trial, 1988 Does a low-fat diet reduce symptoms of cyclical breast pain? Yes. After 6 months on a low-fat diet, women had significant reduction in premenstrual breast tenderness and swelling. On physical exam, 6 of 10 women in the diet group showed improvement compared to 2 of 9 in the control group. Survey study, 1988 Do women crave sweets before their period, and is it linked to mood changes? Yes, food cravings around the period are real and cyclical in most women. However, they are not linked to mood changes or mood severity. Randomised trial, 1988 Does tamoxifen help severe premenstrual breast pain? Yes. Eighty-nine percent of women treated with tamoxifen were free of symptoms compared to 38% on placebo. Twelve months after treatment, 53% of the tamoxifen-treated women remained symptom-free versus none of the placebo group. Randomised trial, 1987 Does progesterone suppository help premenstrual syndrome? No, progesterone vaginal suppositories (200 mg) did not reduce PMS symptoms more than placebo. This was a small study of 30 women. Review, 1986 How should breast pain from PMS be treated? Breast pain is part of PMS. Many treatments exist but we do not have clear evidence about which ones work. Survey study, 1986 How common are premenstrual symptoms in women? Very common. About 70% of women reported mental symptoms in combination with body swelling. Premenstrual anxiety increased with age. Case-control study, 1984 Do women with breast pain during their menstrual cycle have higher prolactin levels? No, the study found no difference in prolactin levels between women with breast pain and healthy women, so high prolactin does not appear to cause this symptom. Study, 1984 Do women with PMS actually gain weight or bloat, or is it just how they feel? Women with PMS report feeling bloated during the premenstrual phase, but actual body weight and body measurements do not increase. The sensation appears to be a change in how women perceive their bodies, not an actual physical change. Randomised trial, 1982 Is bromocriptine or norethisterone more effective for premenstrual syndrome? Bromocriptine reduced breast engorgement, irritability, and total symptoms more than placebo, while norethisterone only helped breast tenderness. Bromocriptine worked better but had more side effects. Survey study, 1982 How common are premenstrual symptoms in American women, and what factors affect them? Premenstrual symptoms are very common in American women, with over 30% experiencing weight gain, headache, mood changes, and other symptoms, though only 2% to 8% found them severe. Randomised trial, 1980 Does bromocriptine help premenstrual tension? Bromocriptine improved breast tenderness, bloating, and depression, but placebo also helped with many other symptoms, so the true effect may be smaller than it appears. Study, 1976 Do mood and body changes happen at the same time in the menstrual cycle? Women experience more pain and water retention during their period and just before it, but their mood problems and stress responses are more strongly tied to what's happening in their lives than to their cycle. Men have more stable emotions and less pain throughout. Study, 1975 Does water retention in the body cause breast pain? A study of 56 women measured body water levels at different times in their menstrual cycle. Most women did not show the expected increase in water before menstruation, and changes in water did not match whether women had breast pain. Non-randomised trial, 1972 Does hydrochlorothiazide help control premenstrual acne? No. A double-blind study of 21 patients found that taking this water pill for 10 days before the period did not reduce premenstrual acne flare-ups. Randomised trial, 2026 Is Pilates exercise more effective than stretching for reducing PMS symptoms? Yes. In this small randomized trial of 20 college students with PMS, Pilates was significantly better than stretching exercises at reducing symptoms. Case report, 2026 Does a personalized homeopathic remedy help treat PMS? In this one 21-year-old woman, yes - a remedy chosen based on her personality type and symptoms led to significant improvement. But this is one person's story, so we can't be sure it would work for others. Non-randomised trial, 2026 Does Brahmighrita (an Ayurvedic herb mixture) help PMS? This abstract does not report any study results. It explains the theory behind why Brahmighrita should help PMS based on Ayurvedic medicine principles, but does not provide findings on whether it actually does. Interview study, 2026 How do women with irregular menstrual cycles experience and manage premenstrual symptoms? Women reported multiple symptoms including mood changes, pain, and bloating, and used various coping methods like pain relievers and heat, but most methods provided only partial relief. The unpredictability of symptoms in irregular cycles caused loss of control and distress. Non-randomised trial, 2026 Does cabbage leaf compress reduce breast pain in women with PMS? Yes. Women who applied cabbage leaf compress for 3 days had a clear decrease in breast pain, while women who received no treatment did not. Survey study, 2026 What factors are linked to PMS in teenagers? Several factors are linked to PMS in teenagers: knowledge about PMS, nutritional status, age of first period, daily behaviors, and stress level. Case report, 2026 Does homeopathic treatment help breast tenderness and irregular periods linked to high prolactin? In this one young woman with high prolactin levels and irregular painful periods, homeopathic treatment over three months reduced breast tenderness, regularized her periods, and improved her energy. We cannot say whether this would help other women or what factors contributed to the improvement. Survey study, 2026 What natural and alternative treatments do teenage women use for acne that happens before their period? 79.9% of teenage women use at least one natural treatment for premenstrual acne, most commonly natural masks, steam baths, and herbal products. They choose these because they believe they are natural and safe. Survey study, 2026 Can changing your diet help with period and PMS symptoms like fatigue, mood swings and bloating? This paper suggests certain foods may help, but it is not a real study on people, it is a write-up of general nutrition advice based on a newspaper health article, so it does not prove anything. Study, 2026 What is premenstrual syndrome and how can it be treated? PMS is a common condition affecting women of reproductive age with mood, emotional, and physical symptoms. It can be managed with lifestyle changes, stress reduction, and medication. Survey study, 2026 Is premenstrual syndrome more common in women with higher body weight? PMS was most common in normal weight women (33%) and overweight women (30%), not clearly linked to obesity (22%). The study cannot explain why. Randomised trial, 2026 Do seed cycling capsules with chasteberry reduce PMS symptoms over two months? Yes, women reported significant improvements in PMS symptoms including pain, cramping, bloating, mood, and sleep. However, this was an open-label study without a control group, so we cannot be sure the improvements are from the product rather than expectation. Survey study, 2026 How common is PMDD in Russian medical students, and what are its symptoms? About 14.3% of medical students had PMDD, or 25.4% including mild forms. Most common symptoms were depression (87.9%), anxiety (48.3%), and sleep problems (31.0%). Cohort study, 2025 Do homoeopathic medicines help PMS symptoms? This abstract does not report study results. It only contains background information about PMS without any actual findings. Survey study, 2025 How common is premenstrual syndrome and what are its main symptoms in female medical students? 77.6% of female medical students have PMS, with the most common symptoms being decreased mood, anxiety, muscle tension, and breast pain. Most women notice symptoms 7-10 days before their period. Non-randomised trial, 2025 Does the pill estetrol/drospirenone ease period pain, bloating and premenstrual mood symptoms? For women trying this pill for the first time, yes, it significantly eased pain, water retention and negative mood. For women switching from another pill, symptoms stayed about the same rather than improving. Survey study, 2025 Can a plant-based supplement reduce PMS symptoms? Yes, a multi-ingredient plant-based supplement taken daily for three months significantly reduced anger, irritability, mood problems, and other PMS symptoms in most women. Without a control group, some improvement might be due to placebo effect or natural changes over time. Survey study, 2025 What factors are linked to PMS in female graduate students? 40% experienced PMS. Stress, period pain, use of menstrual delaying medicine, and earlier menarche were significantly linked to higher PMS risk. Survey study, 2025 Do stretching and relaxation exercises reduce PMS symptoms in adolescent girls? Yes. In 94 adolescent girls who performed stretching and Mitchell relaxation exercises for 12 weeks, PMS symptoms significantly improved. The study found a clear difference between before and after the exercises. Survey study, 2025 How common is PMS among reproductive-aged women, and what are the main symptoms? About 46% had PMS. Anxiety and bloating were the most common symptoms, affecting most of those with PMS. Survey study, 2025 How common is PMS among female medical students, and how severe are the symptoms? PMS is very common in female medical students (71.1%), with most having both emotional and physical symptoms of moderate severity. Survey study, 2025 Is there a relationship between anxiety and PMS in female adolescents? Yes. Adolescents with severe anxiety had 1.6 times higher risk of PMS than those with mild anxiety. Most adolescents in the study had mild anxiety and no PMS. Survey study, 2024 What premenstrual symptoms do martial arts athletes experience? Martial arts athletes experience both disturbing and non-disturbing PMS symptoms with regular 35-day menstrual cycles, and they have no significant difference in PMS compared to non-athletes. Survey study, 2024 What do pharmacy students know about using herbs for PMS? Pharmacy students had moderate knowledge (58.9% correct answers) about these herbs, and about 83% believed the herbs could help PMS symptoms. However, this study only surveyed opinions. It did not test whether these herbs actually work. Survey study, 2024 What factors are associated with PMS and PMDD in adolescent and young women? The study found that mood symptoms (anger, anxiety, irritability), physical symptoms (headache, weight gain), and higher BMI were significantly associated with PMS and PMDD. However, the study had very few cases of PMDD. Survey study, 2024 Do electrolyte levels in the blood affect PMS symptoms? Women with PMS had significantly higher serum sodium levels than those without PMS. However, this was a very small study from one hospital, so we cannot be confident the results apply more broadly. Case report, 2024 Can maca, an herbal supplement, help with PCOS, PMS, dysmenorrhea, and hormone imbalances? In this one woman with PCOS, yes - after three months of taking maca, her PMS symptoms, dysmenorrhea, and hormone levels improved, and these improvements lasted over two years. But this is one person's story, so we can't be sure it works for others. Lab study, 2024 Do physical exercises help women in their 40s and 50s improve strength and flexibility? After 12 weeks of regular exercise (two 60-minute sessions per week), women showed improvements in abdominal strength, hamstring flexibility, and upper body strength. Squats and push-ups were particularly helpful. Survey study, 2024 Is there a link between body weight and PMS? Yes, there is a connection between body mass index and PMS (p=0.00 with a correlation of 0.456). We do not know from this study whether weight causes PMS or if PMS affects weight, or if both are caused by something else. Survey study, 2024 What types of premenstrual syndrome exist and how common are they? Premenstrual syndrome comes in four types: anxiety-type (38%), swelling-type (26%), depression-type (22%), and cravings-type (11%). We can be fairly confident of this, though the study only included students in one Russian city. Survey study, 2024 How common is dysmenorrhea related to PMS in university students, and how do they treat it? About 54% of 320 university students in Karachi experienced PMS-related dysmenorrhea. Most women (93%) used plant-based remedies, while only 7% used standard medications. Survey study, 2024 What premenstrual symptoms are most common in working women? Physical symptoms like breast tenderness, headaches, joint and muscle pain, bloating and weight gain are most common in moderate to severe form, along with fatigue and irritability. Interestingly, sleeping too much is more common than insomnia. Survey study, 2024 How do hormonal changes during the menstrual cycle affect gut health and mood? Hormonal changes during the menstrual cycle affect the bacteria in the gut and mood. Higher progesterone levels in the premenstrual phase are linked with worse bloating, constipation, and mood swings. Approximately 50% to 80% of women experience premenstrual symptoms that affect daily life. Survey study, 2024 Does knowing about Ayurvedic yoga make teenage girls more interested in practicing it for PMS? Yes, teenage girls with more knowledge about Ayurvedic yoga were significantly more interested in practicing it (p=0.00). Survey study, 2024 What are the most common PMS symptoms in medical students and what lifestyle factors make them worse? Anxiety, bloating, and breast tenderness are most common. Coffee drinking, eating sweets, smoking, and heavier periods are linked to worse symptoms, though this doesn't prove they cause PMS. Study, 2024 Can diet changes and probiotics help manage PMS symptoms? This review explores how diet, gut bacteria, and probiotics might help with PMS, noting that the World Health Organization wants low-cost treatments with few side effects. It doesn't present specific research findings yet. Study, 2024 How does traditional Ayurvedic medicine explain PMS? According to Ayurveda, PMS results from an imbalance of bodily elements, particularly a condition affecting something called Apana Vayu, which controls menstrual flow and other body functions. Survey study, 2023 Is higher vitamin C linked to premenstrual symptoms? Higher vitamin C intake was linked to appetite changes. Suboptimal blood vitamin C levels were linked to appetite changes and bloating, but adequate levels were not clearly linked to either symptom. Survey study, 2023 Is there a link between PMS symptoms and how the nervous system controls heart rate? Possibly. Three women showed medium to high connections between their PMS symptoms and heart rate variability throughout the menstrual cycle, especially for mood symptoms. Survey study, 2023 Does childhood trauma increase the risk of PMDD? Yes. Women who experienced childhood trauma were about three times more likely to have PMDD symptoms than those who did not experience childhood trauma. Survey study, 2023 Do hormone levels differ between women with and without PMS? Yes, clear differences. Women with PMS have significantly higher estrogen and lower progesterone compared to those without PMS. Electrolyte levels are similar between groups. Non-randomised trial, 2023 Does mefenamic acid help relieve PMS symptoms? Mefenamic acid relieved PMS symptoms in 70.7% of women, with the most improvement in headache and breast tenderness, but the study had no control group so we cannot be certain the drug itself caused the improvement. Survey study, 2023 Does pelvic alignment exercise help with period pain and PMS symptoms? Yes, for some symptoms. The exercise program reduced period pain and improved mood-related PMS symptoms, and also improved pelvic positioning. Survey study, 2023 What symptoms does PMS cause and how common is severe PMS? PMS can cause around 150 different symptoms ranging from cramps to mood changes to fatigue. About 3-8% of women experience premenstrual dysphoric disorder, which is a more severe form than typical PMS. Case report, 2023 Does acupuncture combined with supplements and meditation help PMS? A 36-year-old woman with long-standing PMS saw major improvement in her symptoms after combining acupuncture treatments with several supplements and daily meditation. However, this is just one case, so we do not know which parts of the treatment helped most. Survey study, 2023 What oral symptoms do women experience before their period? Dry mouth affects 29.9% of women in the premenstrual phase, followed by taste changes (25.3%) and swelling sensations (18.4%). The study had no control group to compare with women who don't have PMS. Study, 2023 What is the difference between period pain and premenstrual syndrome? Period pain and PMS are different conditions. Period pain is throbbing, cramping in the lower abdomen with back pain, nausea, diarrhea, and headaches. PMS causes weight gain, bloating, irritability, and fatigue starting 1 to 2 weeks before the period. Survey study, 2023 Does exercise help reduce premenstrual syndrome symptoms? Exercise may reduce PMS symptoms including pain, fatigue, mood problems, and water retention, according to several studies. However, the existing research is limited and inconclusive about which types and amounts of exercise work best. Survey study, 2023 What is PMS and PMDD, how common are they, and how are they usually treated? PMS is very common, affecting almost half of women of reproductive age worldwide, and most cases are mild to moderate, while PMDD is a more severe, officially recognized psychiatric form; treatment usually starts with lifestyle approaches and moves to medication like SSRIs for severe cases. Survey study, 2023 What percentage of women aged 20-35 have PMS symptoms and what types are most common? This survey of 252 women found that about half (45.2%) report moderate PMS symptoms and 40.1% report mild symptoms. The most common physical symptoms are breast tenderness and swelling (52.8%), skin lesions (44%), and cravings for salt or sugar (40.9%). Systematic review, 2023 Can relaxation methods like yoga help with the anxiety that comes with PMS? This review suggests relaxation therapy, including yoga, may help lower anxiety linked to premenstrual syndrome, but it mostly draws on older studies rather than new data, so confidence in this is limited. Survey study, 2023 Does PMS affect school performance and relationships in female medical students? Yes, significantly. 73.6% of the 2080 students studied had premenstrual symptoms, and those with symptoms did worse in school and had more problems with relationships. The study shows a clear link, but only studied medical students. Survey study, 2023 Should doctors classify menstrual headaches based on how often they happen? Yes. Headache frequency and purity (whether it happens only around menstruation) should both be considered because they affect how severe the headaches are and what type they are. High-frequency headaches are more severe and similar to migraine. Non-randomised trial, 2022 Does a topical gel help acne around your period? Yes, the combination gel improved period-related acne in all 22 women with no serious side effects. The study was very small with no comparison group. Non-randomised trial, 2022 Does eating papaya help premenstrual tension syndrome? We cannot tell if papaya helps because the abstract does not report the actual results. The study was small and not properly randomized. Survey study, 2022 Does green tea reduce physical PMS symptoms? Women who drank 3 cups of green tea daily for 3 months reported improvement in physical symptoms like bloating and acne. However, there was no control group, so we cannot be certain green tea caused this improvement. Survey study, 2022 Did COVID-19 stress worsen period pain and PMS symptoms in female medical students? Yes. Severe period pain increased from 36.9% before COVID-19 to 49.9% during the pandemic, and period symptoms were closely linked to depression and anxiety. Study, 2022 What are the symptoms, causes, and treatments of PMS and PMDD? PMS affects 20-40% of menstruating women and causes fatigue, mood changes, and bloating. PMDD is less common but more severe. Possible causes involve hormone changes and brain chemistry. Treatments include lifestyle changes and medications. Survey study, 2022 How common is PMS in female medical students and how does it affect their ability to study? PMS was present in 37% of medical students. It significantly reduced their study time, work productivity, concentration, and exam performance. Survey study, 2022 How common are PMS and PMDD in university students and what factors increase the risk? Nearly half of university students have PMS (46.9%) and about 1 in 10 have PMDD (11.1%). Depression, recent alcohol use, and being a first or second year student are risk factors. Survey study, 2021 How many college students know about PMS symptoms? 90% of students were aware of PMS symptoms, but 10% were not. The study was very small and did not measure knowledge deeply. Survey study, 2021 What is PMDD and how common is it compared to regular PMS? PMDD is severe PMS with psychological, behavioral, and physical symptoms that happen cyclically. It affects 1-10% of women, while 3-30% have PMS that interferes with daily life. The difference depends on how severe symptoms are and how much they disrupt life. Survey study, 2021 How common is PMS in health care workers? Very common at 76% overall. But rates were much higher in younger women: 80% of those ages 20-24, dropping to 58.3% in ages 25-30, and 46.6% in ages 31-40. Survey study, 2021 Is PMS linked to physical activity, weight, and blood pressure? Yes. Women with regular physical activity, normal weight, and no high blood pressure had significantly fewer PMS symptoms. Survey study, 2021 How common are premenstrual symptoms and do they affect emotional well-being? Nearly all women (96.8%) experience at least one premenstrual symptom. Those with more symptoms report significantly worse emotional well-being. The more symptoms a woman has, the greater the negative impact on how she feels. Survey study, 2021 How common are premenstrual symptoms in female medical students, and how severe are they? About 30% have premenstrual symptoms, mostly mild. Psychological symptoms like irritability are more common than physical ones. Survey study, 2021 Do premenstrual symptoms affect sexual desire? Sexual desire is linked to some premenstrual symptoms, particularly back pain, painful periods, and mood changes. Sexual desire was not clearly linked to other symptoms like headaches or breast tenderness. Survey study, 2021 Do PMS symptoms affect exam scores in medical students? Some PMS symptoms affected exam scores differently. Students with acne had higher exam scores, while those with sleep problems, nausea, bloating, or skin changes had lower exam scores. This is a small study from one university. Survey study, 2021 Does dancing or running reduce premenstrual symptoms? Dancing (Argentine tango) modestly reduced the duration of premenstrual symptoms, but running did not show the same benefit. Neither activity eliminated symptoms completely. Survey study, 2021 Does nutritional status affect PMS symptoms? Yes, there is a clear relationship between nutritional status and whether a woman experiences PMS. However, the study does not specify which nutrients matter most. Survey study, 2020 How common is premenstrual syndrome in young females? The study does not report the exact prevalence percentage. It confirms that PMS symptoms are common in young women and often limit their daily activities. Survey study, 2020 How do diet and lifestyle factors relate to PMS and PMDD in medical students? Alcohol and tobacco use were linked to PMDD. Diet type was not linked to PMS or PMDD. Anger and irritability were the most common symptoms. Cohort study, 2020 Do SSRIs help women with both PMS and depression? Women with both PMS and depression who took SSRIs showed improvement over 6 months. However, the evidence is weak because this was a small study without a control group. Survey study, 2020 How do women's feelings about their bodies affect their PMS distress? Women's distress from PMS is connected to how they feel about their changing bodies during the menstrual cycle, especially feelings of discomfort with weight and appearance. Psychological therapy that helps women accept these changes can reduce this distress. Survey study, 2020 Do oral contraceptive pills increase the risk of premenstrual syndrome symptoms? Yes. Women taking oral contraceptive pills had about 21 percent higher risk of premenstrual symptoms than non-users, and this effect was stronger in women age 25 and older, where the risk increased by 32 percent. Survey study, 2020 What are the most common PMS symptoms and how much do they disrupt daily life? Painful periods affected 63% of women and 40% said their routine was disrupted during their period. However, the study was in one community in Pakistan and only recorded current symptoms, not tracked changes over time. Survey study, 2020 Do girls with type 1 diabetes experience different PMS than other girls? No clear difference. Most girls with type 1 diabetes (71.4%) experience no to mild PMS symptoms, regardless of how well their diabetes is controlled. Survey study, 2020 How common are premenstrual symptoms in secondary school students? Very common: 82.5% had mood swings or nervousness and 80.1% had fatigue. Educational level and age were associated with symptom severity. Survey study, 2020 How common is PMS in elite female athletes, and do training or lifestyle factors cause it? 14.55% of elite female athletes have moderate to severe PMS. No specific modifiable risk factors were found. 76.6% of athletes felt their symptoms interfered with performance, but only 5 out of 18 athletes with PMS saw a doctor. Study, 2020 What is premenstrual syndrome and what causes it? PMS is a group of physical and emotional symptoms caused by the body's abnormal response to hormone changes during the menstrual cycle. Symptoms always go away when the period starts. Survey study, 2019 Are PMS symptoms linked to how women feel about their health and stress? Yes. Women who reported feeling unhealthy or stressed had much more severe PMS symptoms. How a woman perceives her own health was the strongest factor linked to PMS symptom severity. Cohort study, 2019 What factors cause PMS in women of reproductive age? Age was the main factor, explaining 90.3% of PMS cases. Other factors linked to PMS were higher parity, older age, poor nutrition, and less exercise. Cohort study, 2019 Why do some women's legs feel heavy and swollen before their period? The study found that women with premenstrual leg heaviness have enlarged leg veins during the later part of their menstrual cycle. Vein swelling and backward flow occur during this time, which explains the heaviness and swelling. Survey study, 2019 What are the best ways to manage PMS? PMS is managed in four steps: create awareness and make lifestyle changes, then offer therapy and complementary treatments, then medication if needed, and rarely surgery. This summarizes international guidelines but doesn't show strong evidence about which approach works best. Survey study, 2019 Do women with acne flares before their period have higher oxidative stress? Women with premenstrual acne flares had higher oxidative stress markers. A clear relationship was found between measurements on day 1 and day 21 of the cycle. Study, 2019 Can diet help prevent or reduce PMS symptoms? Diet appears to play a role in PMS. Getting enough vitamins, minerals, and carbohydrates may help reduce symptoms, while skipping meals and eating junk food may make symptoms worse. Survey study, 2019 How common is premenstrual syndrome among medical students? About 3 out of 4 medical students in this study had PMS. Mood swings and anxiety were most common. Survey study, 2019 How common is PMS in female operating room technologists? The study aimed to find how common PMS is in female operating room technologists and what factors influence it, but the results are not provided in this abstract. Survey study, 2019 Does PMS affect how satisfied women are in their marriages? Yes. Women with PMS reported significantly higher marital dissatisfaction than those without PMS. Survey study, 2018 How common is PMS in teenage girls? PMS is very common in adolescent girls. Around 70% experience abdominal bloating and breast tenderness, 38% experience mild anxiety, and over 22% experience severe mood swings. Survey study, 2018 How common is PMS among female university students in Nigeria? Very common. In this study, 42.9% of students met the criteria for PMS, and almost half of those (47.6%) had severe PMS or PMDD. Survey study, 2018 How aware are men of what PMS is and how it affects their partners? This abstract only describes the background and purpose of the study; it does not give the actual results on men's awareness, attitude, or behavior regarding PMS. Study, 2018 What does traditional Unani medicine teach about treating PMS? This article reviews traditional Unani medicine approaches to PMS, but doesn't report on any research study testing whether they work. Survey study, 2018 Do women who attempt suicide experience more menstruation-related problems? More than half of women who attempted suicide reported premenstrual distress symptoms for two menstrual cycles. The study cannot prove menstrual problems caused suicide attempts, but suggests a possible connection. Survey study, 2018 How does PMS affect self-esteem in girls? Girls with PMS showed lower self-esteem compared to expected levels. The link may be because PMS mood changes lead girls to feel worse about themselves. Study, 2018 Does glutathione change during the menstrual cycle and affect premenstrual acne? Yes. A protective substance in the blood called glutathione decreased by day 21 of the menstrual cycle. This decrease was linked to worse acne before menstruation. Survey study, 2018 Do Asian and Caucasian women experience different PMS symptoms? Yes. Asian women reported significantly higher rates of mood swings, depression, food cravings, digestive problems, and menstrual cramps, and had shorter menstrual periods. Study, 2018 Does treating gas and bloating with nystatin help premenstrual syndrome? According to this author, yes. Using nystatin (an antifungal medication) to treat gas and bloating may also improve other PMS symptoms. Interview study, 2017 What psychiatric symptoms do women experience around their period? Irritability is the most distressing symptom (66 percent), followed by bloating (18 percent) and breast pain (16 percent). Symptoms last 6 to 10 days during the premenstrual phase and improve when menstruation begins. Randomised trial, 2017 Does yoga help with PMS symptoms? This text only gives the background and reasoning for a yoga trial. It does not include the trial's actual methods or results, so no answer about whether yoga worked can be given from this excerpt. Randomised trial, 2017 Can chasteberry (Vitex agnus castus) help premenstrual breast pain and PMS? Based on a review of earlier placebo-controlled studies, chasteberry extract seems to ease premenstrual breast pain and some PMS symptoms, likely by lowering prolactin. Side effects were mild and infrequent, but this is a summary of past research, not a new trial. Survey study, 2017 How many young women have premenstrual syndrome? The abstract is mostly in Polish and incomplete, so we cannot give a clear answer about prevalence from the available text. Survey study, 2016 Are low vitamin D levels or certain dairy-related genes linked to premenstrual symptoms? Some women with low vitamin D are more likely to experience clumsiness and confusion before their period. A genetic variation affecting how your body digests dairy is also linked to more clumsiness but fewer cramps. Survey study, 2016 Does 12 weeks of yoga help premenstrual symptoms? Yes, 12 weeks of yoga was associated with improvements in menstrual pain, emotional symptoms, and physical symptoms. Women used fewer painkillers and reported less impact of pain on work, though this was a small study without a control group. Survey study, 2016 How common is PMS in Pakistani university students and what are the main symptoms? PMS is common, affecting 60% of the 520 students studied. The most frequent symptoms were fatigue (86.84%), irritability (71.05%), and breast tenderness (67.65%). Survey study, 2016 Does stress increase premenstrual syndrome in college students? Yes. Female college students who experienced stress were more likely to have premenstrual syndrome than those without stress. 34.9 percent had stress and 32.8 percent had PMS symptoms. Survey study, 2016 Is depression linked to PMS in college women? Yes. Women with higher depression levels tend to have more severe PMS. This is observational, so depression may not cause the PMS. Survey study, 2015 How common is PMS in teenage school girls in an urban city in India? 54% of the teenage girls reported PMS symptoms, with irritability being the most common symptom (88.1%). Because this is a survey, it reflects what girls reported rather than clinical diagnosis. Non-randomised trial, 2015 Does dark chocolate reduce PMS symptoms? Yes, eating dark chocolate daily for 2 weeks before menstruation reduced most PMS symptoms including anxiety, fatigue, and cramps in this small study. However, acne slightly worsened. Survey study, 2015 Is PMDD linked to postpartum depression? Yes, strongly. Among women with postpartum depression, 34.8% had PMDD, compared to only 4.9% without postpartum depression. This suggests a hormonal connection between the two conditions. Cohort study, 2015 Can a procedure to treat heavy periods also ease premenstrual symptoms like bloating and mood swings? In this small study, women reported clear improvement in all 6 premenstrual symptoms up to a year after endometrial ablation, but without a comparison group we can't be fully certain the procedure itself was the cause. Interview study, 2015 What are the symptoms of PMDD and how many women have it? PMDD is a severe form of premenstrual syndrome. About 90% of women experience premenstrual symptoms, but only 4.6% to 6.4% meet criteria for PMDD, and about 5% experience severe symptoms. Survey study, 2015 Does regular running reduce PMS symptoms? Yes. Women who ran regularly 3 times a week for 20-45 minutes had much fewer PMS symptoms than women who didn't exercise, including less pain, fewer mood changes, and less bloating. Case report, 2015 Can endometriosis develop in the Bartholin gland? Yes, endometriosis can develop in the Bartholin gland. It may be mistaken for a cyst but can be correctly diagnosed using ultrasound imaging. Survey study, 2015 How common is PMS among teenage girls in rural India? Very common: about 6 in 10 girls in this rural school reported PMS, with irritability, anxiety and anger as the most frequent symptoms. Survey study, 2015 How common is PMS in Turkish medical students and does it affect quality of life? PMS is very common in Turkish medical students (91.8%), and those with severe PMS have the lowest quality of life scores. Randomised trial, 2015 Can Vitex help a woman with high prolactin levels and irregular periods? Yes, in this one case. A woman with mild high prolactin who could not tolerate standard treatment improved with Vitex. But this is only one patient, so we cannot know how well it works for others. Review, 2014 Do birth control pills help PMS? Yes. Birth control pills can treat and prevent premenstrual syndrome according to this review, though the abstract does not provide specific details about the strength of benefit. Survey study, 2014 Which PMS symptoms tend to occur together? Different PMS symptoms commonly occur together. Women who have mood symptoms like anxiety and irritability also tend to have appetite changes, depression, and sleep problems, and these associations were found to be statistically significant. Review, 2014 How is breast pain in PMS treated? Breast tenderness (mastodynia) is a common cyclic symptom of PMS and more severe in PMDD. Treatment can focus on relieving symptoms or changing the menstrual cycle. Medications including SSRIs are used as pharmaceutical options. Interview study, 2014 Does acne get worse around women's periods? About two-thirds of adult women with acne reported that their acne gets worse around their period, with more than half saying it worsens in the week before their period starts. Survey study, 2014 How common are PMS and PMDD in middle-aged women going through perimenopause? Approximately 95% of perimenopausal women had PMS and 23% had PMDD. Women with PMDD were significantly more likely to have severe menstrual pain. Randomised trial, 2013 Does a supplement with krill oil, vitamins, and plant ingredients help PMS symptoms? Yes. All 29 women reported significant improvement in 10 PMS symptoms after 3 months. However, this open-label study had no control group, so improvement might partly be due to placebo effect. Randomised trial, 2013 Does homeopathic treatment reduce PMS symptoms? In this small study, homeopathic treatment was associated with symptom reduction and improved quality of life. However, there was no control group, so we cannot be certain the improvement was due to the treatment rather than placebo effect or natural improvement. Cohort study, 2013 Does this birth control pill help premenstrual symptoms? Yes, in women with severe premenstrual mood symptoms, this birth control pill improved negative mood, positive mood, swelling, and effect on daily life. Women with no, mild, or moderate symptoms did not benefit. Survey study, 2013 How common is acne that gets worse before your period? Very common. About 3 in 4 women with acne get new spots before their period, usually 7 days or 2-3 days before menstruation starts. Case report, 2012 How can doctors tell the difference between severe PMS and bipolar disorder? Doctors can tell the difference by looking for symptoms that clearly follow the menstrual cycle and improve during pregnancy. These patterns occur in severe PMS but not in bipolar disorder, and severe PMS doesn't respond to antidepressants or mood-stabilizing medications used for bipolar disorder. Survey study, 2011 Do overweight or obese women have worse PMS than normal weight women? Yes. Overweight and obese women reported significantly more pain and mood-related PMS symptoms compared to normal weight women. Review, 2011 When should acne comedones be extracted to treat premenstrual acne? An expert proposes extracting comedones at ovulation to prevent the skin changes that trigger period-related acne. However, this proposal has not been tested in a clinical trial, so there is no evidence it works. Review, 2010 Does the EE/DRSP birth control pill with shorter placebo days reduce PMS symptoms? The EE/DRSP pill with 24 days of hormones and 4 days of placebo appears to reduce PMS and withdrawal symptoms including mood changes, breast tenderness, headache and pelvic pain. The evidence comes from clinical trials but specific numbers of improvement are not given. Survey study, 2010 What causes or increases the risk of premenstrual acne? Mental stress, spicy and fried foods, stomach problems, family history, and hormone-related issues showed a clear relationship with worse premenstrual acne. Age and season did not show a clear relationship. Survey study, 2010 Is living in a less wealthy neighborhood linked to worse premenstrual symptoms? Higher neighborhood socioeconomic disadvantage was clearly linked to more premenstrual pain even after considering other factors, though other premenstrual symptoms showed no clear link. Survey study, 2010 How do mood, physical state, and self-image change during the premenstrual period? During the premenstrual period, women experienced more negative emotions, fewer positive emotions, and felt worse about their body and themselves. Changes affected how they saw themselves, not just their mood. Case report, 2009 Can PMS cause cheek biting and swelling? In this one case, yes. A woman's cheek biting and swelling happened before her period along with other PMS symptoms. Randomised trial, 2009 Does toremifene reduce premenstrual breast pain? Yes, toremifene reduced premenstrual breast pain compared to placebo in this 10-woman study, and MRI scans showed measurable changes in breast tissue. However, the study was small and some results were inconsistent. Review, 2009 How common are PMS and PMDD, and how much do they disrupt women's lives? PMS causes distress in up to 20% of women and severe work or relationship problems in 3-8%. Women with PMDD experience about 3000 days of severe symptoms over their reproductive years. Survey study, 2008 Does eating lower glycemic index carbohydrates help reduce PMS symptoms? Yes. Lower glycemic index diet was associated with fewer overall PMS symptoms and specifically with fewer concentration problems, autonomic reactions, and water retention. Study, 2008 What causes severe PMS and how is it treated? Severe PMS is caused by the body's reaction to normal hormone changes during the menstrual cycle. It is treatable with hormonal methods or antidepressants. Study, 2008 Does rifaximin help with IBS symptoms that worsen during PMS? In these 3 women, taking rifaximin during the premenstrual phase improved their IBS symptoms including bloating, pain, and diarrhea. The improvement continued across multiple menstrual cycles, suggesting the treatment may have lasting benefit. Review, 2007 Is drospirenone an effective ingredient in birth control pills for PMDD? Birth control pills containing drospirenone appear safer and better tolerated than other low-dose pills for mood changes, acne, and severe PMS (PMDD), with similar overall safety profiles. Non-randomised trial, 2007 Can a birth control pill with ethinylestradiol and drospirenone reduce water retention in PMS? The pill significantly reduced total body water and extracellular water after 6 months. This was a small study without a placebo control, so we cannot be certain the improvement was due to the pill. Review, 2007 Can birth control pills be tailored to help PMS while reducing side effects? Newer low-dose pills may reduce water retention and weight gain. The right choice depends on each woman's body type and symptoms. Randomised trial, 2006 Does a five-day gradual reduction of chlormadinone help PMDD symptoms? Yes, significantly reducing anxiety and depression and some other symptoms by the third month of treatment. This is a small pilot study, so larger trials are needed to confirm. Cohort study, 2006 How should severe period pain in teenagers be treated? Regular pain relief medication (NSAIDs) started before periods begin may help. In one teenager, severe pain improved from 8 out of 10 to 5 out of 10. Survey study, 2006 Do menstrual cycle symptoms affect how well people with HIV stick with their medications? A 12-week study of 54 HIV-positive women found that certain menstrual cycle symptoms got worse at specific times and women were slightly less likely to take their antiretroviral medications during menstrual weeks. Survey study, 2005 Does drospirenone hormone therapy reduce weight gain and PMS-like symptoms? In studies of drospirenone-containing hormone therapy, women had less or no weight gain (mean decrease of 1.2 kg after one year) and improvements in bloating, swelling, breast tenderness, and mood. Review, 2005 What causes breast pain and how is it treated? Breast pain affects up to 2 out of 3 women and can be associated with PMS. It is usually benign, and most women do not need treatment. Non-randomised trial, 2005 Do women with PMS have abnormal automatic nerve function? No significant differences were found in sympathetic nerve function between women with PMS and healthy women across their cycle. This suggests PMS is not caused by problems in this particular automatic nerve system, though only one type of test was measured. Randomised trial, 2004 Does rofecoxib reduce premenstrual acne? Yes. Rofecoxib was more effective than placebo at reducing premenstrual acne. Survey study, 2004 Do women get more acne before their period? Yes, most women (63%) had a 25% increase in acne lesions before their period. But this was a small study without a comparison group, so we should be cautious about how much this applies to all women. Survey study, 2003 How common is PMDD in women in Bosnia and Herzegovina and what are the most common symptoms? 52% of women in Bosnia and Herzegovina met diagnostic criteria for PMDD. The most common symptoms were depressed mood (68%) and breast swelling or weight gain (81.8%). Survey study, 2002 How common is premenstrual dysphoric disorder among women in Morocco? About half of 618 women interviewed in Casablanca met criteria for PMDD, with the most common symptoms being appetite changes, depressed mood, and emotional instability. Review, 2002 What supplements or alternative treatments help PMS symptoms? Several supplements show evidence for helping PMS: calcium, magnesium, vitamin E, thiamine (vitamin B1), and omega-3 fatty acids. Japanese herbal formulas may also help. Review, 2002 Can a birth control pill with drospirenone help PMS symptoms and quality of life? This review discusses that a birth control pill containing ethinyl estradiol and drospirenone may help certain PMS symptoms because drospirenone can reduce water retention and other premenstrual distress. However, the review does not provide specific data on how well it works. Survey study, 2002 Does the menstrual cycle change gut sensitivity in women with IBS? Yes. Women with IBS have more sensitive bowels during their period compared to other times, which may explain why their IBS gets worse. Women without IBS do not show this change. Survey study, 2001 How does a woman's attitude toward menstruation relate to her premenstrual symptoms? A clear connection was found between how women view menstruation and their premenstrual symptoms. Women who saw menstruation as weakening them physically and emotionally experienced more premenstrual symptoms. Survey study, 2001 Is acne linked to polycystic ovary syndrome, and do these conditions go with PMS? Yes. High male hormone levels in PCOS cause acne, and in 93% of women with both conditions, acne severity matched PCOS severity and the presence of PMS. Cohort study, 1999 Is cyclical breast pain always a sign of premenstrual syndrome? No. In this study, 82% of women with regular monthly breast pain did not meet criteria for PMS, suggesting cyclical breast pain is often a separate condition. Study, 1999 Does vitamin B6 help with PMS symptoms? About 5% of women who ovulate experience multiple premenstrual symptoms. Vitamin B6 has been recommended for these symptoms, though the available information is limited. Survey study, 1998 What is the best way to measure breast pain that comes and goes with your period? A daily visual pain scale works much better than asking women to remember their pain later. Women with cyclical breast pain reported much higher pain levels during menstruation (5.3 out of 10) compared to women without cyclical pain (3.5). Case-control study, 1997 Do women with severe breast pain and swelling have worse PMS symptoms? Yes. Women with cyclic mastopathy reported more severe PMS symptoms, especially water retention and breast symptoms, as well as mood changes, behavior changes, and concentration problems. Case-control study, 1997 Are PMDD and eating disorders related? Possibly. PMDD and eating disorders share high rates of mood and anxiety disorders and a personality trait called harm avoidance, but this small study cannot confirm they share a common cause. Guideline, 1997 Can a hormone test predict which women will respond to bromocriptine for cyclical breast pain? Yes. Women with an abnormal prolactin response to a hormone test were much more likely to improve with bromocriptine than those with normal response (73.6% versus 23.5%). Non-randomised trial, 1996 Do women with PMS have different hormone levels? Women with PMS have lower vasopressin levels throughout their cycle, suggesting a biological difference. However, this very small study needs larger confirmation studies. Survey study, 1996 Are women happy taking the birth control pill and what side effects do they experience? Most women are happy with the pill. Periods become shorter and lighter, though some experience weight gain and breast tenderness. Cohort study, 1996 Does lisuride maleate, a dopamine medication, reduce PMS symptoms? Symptoms improved significantly, with headaches dropping from 85.7% to 20% and other symptoms also improving. However, this was a small study with no control group, so we cannot be sure how much improvement came from the drug versus placebo. Survey study, 1995 Do diet and exercise affect menstrual symptoms? Yes. During the time before and during your period, higher carbohydrate intake was linked to worse mood and less activity. Lower protein was linked to better mood, and more aerobic exercise was linked to fewer symptoms. Survey study, 1995 Do PMS symptoms affect how well women work? Yes. Over half of working women (57%) said their PMS symptoms affected job performance, and 40% felt less productive during premenstrual symptoms. Mood-related symptoms like irritability, anger, and depression had the strongest link to reduced work performance. Review, 1994 What causes functional bloating (bloating with no clear medical cause) and how can it be treated? The cause is unknown. Old explanations have been disproven, and newer ideas suggest recent weight gain, weak abdominal muscles, or fluid trapped in the small intestine. No treatment has been proven to work. Survey study, 1994 What symptoms do teenage girls experience, and do symptoms change during their menstrual cycle? Yes. Girls reported physical and emotional symptoms that were more intense during their period. Girls from the larger city reported more intense symptoms overall than girls from the medium-sized city. Survey study, 1993 Which menstrual symptoms are most common and how do lifestyle and age affect them? Bloating, backache, and headache are the most common. Symptoms vary significantly based on education level, whether you live in a city or rural area, age, and weight, suggesting both biology and lifestyle matter. Review, 1993 Is low brain serotonin linked to mood swings and the weight gain and carb cravings that can come with them? This review argues that brain serotonin plays a role in linking mood changes to carbohydrate cravings and weight gain, and that treatments which raise serotonin activity can improve both mood and eating control, but it is a summary of past research, not a new study. Study, 1993 Do women with PMS have different fluid shifts in their bodies during their cycle? Yes, women with PMS show evidence of fluid moving differently through their bodies during the second half of their cycle, though their total body weight doesn't change. Non-randomised trial, 1993 Does stopping menstruation with a GnRH agonist reduce PMS symptoms? In women with PMS alone, yes. Six of seven had significant symptom reduction including near-complete relief of premenstrual depression. In women with PMS and depression, the treatment did not help. Survey study, 1993 How common is premenstrual tension among nurses in Kenya? Very common. 95.5 percent of 400 nurses studied reported premenstrual tension, with breast tenderness and bloating being the most frequent symptoms. Survey study, 1992 How should doctors diagnose premenstrual syndrome? PMS diagnosis should include mood symptoms like irritability, anxiety, depression, or fatigue, along with a physical symptom like bloating or breast tenderness. Doctors need to ask women about symptoms every day for a full cycle, not rely on blood tests or personality assessments. Survey study, 1991 How common are menstrual symptoms in working women? The most common symptoms were weight gain and swelling (over 60% of women), followed by anxiety, tension, irritability, fatigue, cramps, breast pain, mood swings, and food cravings. Symptoms were more common in younger women. Lab study, 1990 What are the different patterns of premenstrual symptoms women experience? Women have different combinations of premenstrual symptoms. The group with breast tenderness, bloating, irritability, tension and depression together was most likely to rate their symptoms as severe. Randomised trial, 1990 Does synthetic diosmin help premenstrual breast pain? Yes, synthetic diosmin significantly reduced breast pain over one year and the improvement lasted. However, this study had no placebo group, so we cannot tell if the benefit is from the drug itself or other factors. Review, 1990 What is PMS and how is it treated? PMS is a group of physical and emotional symptoms that start 5 to 8 days before menstruation and disappear 34 to 48 hours after the period begins. Many treatments including hormones, vitamins, and other medications can help. Survey study, 1990 Is premenstrual bloating different from bloating at other times of month? Not really. Daily changes in weight and tummy size were similar whether it was premenstrual or not, suggesting mild bloating is just a normal, everyday experience for many women rather than a separate 'abnormal' condition. Cohort study, 1989 Are soccer injuries more common at certain times of the menstrual cycle? Women soccer players had more traumatic injuries during the premenstrual and menstrual period compared to other times in their cycle, especially if they had symptoms like irritability, breast swelling, or abdominal swelling. Women using birth control pills had significantly fewer injuries. Study, 1988 Does fluid around the brain change before your period? Yes, fluid around the brain increased in nearly all women before menstruation. However, this happened because the brain itself became slightly smaller, not because the brain was swelling. Randomised trial, 1987 Does danazol help premenstrual tension symptoms? Danazol may help some symptoms better than placebo, particularly breast pain, lethargy, anxiety and increased appetite by the third month. However, 13 of 40 women dropped out during the study, mostly because they felt the treatment was not helping. Review, 1987 Does spironolactone, a water pill, help with premenstrual syndrome symptoms? Some well-designed studies found that spironolactone helped reduce bloating and belly swelling during PMS. It may also improve mood and emotional symptoms. Survey study, 1987 How common are premenstrual symptoms in the community? Very common, ranging from 39 percent for breast swelling to 81 percent for weight gain. Socioeconomic status, race, and breast disease history were linked to more symptoms. Cohort study, 1986 Is PMS mainly about symptoms worsening before your period, or is there more? Women with PMS have higher depression, anxiety, and tension even in the early part of their cycle. Some symptoms do worsen premenstrually, but baseline mood appears to be the bigger issue. Survey study, 1986 Can nutrition and diet changes help with PMS symptoms? Research on the nutritional theory of PMS is controversial, but practical diet changes may help. Eating balanced meals, limiting salt and caffeine, choosing complex carbohydrates over refined sugar, and getting enough calcium may improve symptoms. Large supplement doses are not recommended. Survey study, 1985 What causes cyclical breast pain, and is it related to fibrocystic disease? Fibrocystic disease doesn't cause cyclical breast pain. The exact cause is unknown, but researchers believe it originates in the breast tissue itself rather than in hormone-producing organs. Survey study, 1985 What is premenstrual syndrome and how is it treated? Premenstrual syndrome is a collection of physical and emotional symptoms that affect 5 to 20 percent of menstruating women. Treatment options include lifestyle changes, counseling, medication, and birth control pills, and satisfaction with treatment is commonly achievable. Case report, 1985 What is PMS and how should doctors treat it? PMS is a cyclical condition with physical and psychological symptoms that occur 7-14 days before menstruation. About 30 percent of women experience PMS in a severe form at some point in their lives. Study, 1983 Does nutrition affect premenstrual symptoms? Yes. Different types of premenstrual symptoms may respond to different nutritional approaches: vitamin B6 (200-800 mg per day) for anxiety and water retention, magnesium for appetite and cravings, and limiting salt (to 3 grams per day), caffeine, and nicotine. Non-randomised trial, 1983 Do drugs that block prostaglandins help PMS? This paper proposes that prostaglandin-blocking drugs might help PMS based on a theory, but it does not present results from a clinical trial. Survey study, 1982 What percentage of women have premenstrual tension symptoms? Half the women in the study had at least one type of premenstrual tension symptom. Anxiety and mood changes, and swelling and bloating, were the most common types. Survey study, 1982 Are premenstrual and menstrual symptoms separate problems or part of one larger problem? They appear to be part of one larger problem. Although some symptoms are worse before your period and others during it, the symptoms largely overlap. Study, 1980 Does dydrogesterone (Duphaston) help premenstrual syndrome symptoms? Dydrogesterone helped relieve depression, headache, swelling, and irregular bleeding in women with PMS, but did not help with breast tenderness. Most women wanted to continue taking it. Study, 1975 Does bromocryptine help with breast pain? A study of 15 women with breast pain treated them with bromocryptine for 2 to 4 weeks. Ten recovered completely, 3 improved somewhat, and 2 saw no benefit. Study, 1973 Do opipramol and chlorthalidone help treat PMS? Yes, both treatments showed improvement in PMS symptoms. The combination of opipramol and chlorthalidone worked better than opipramol alone, particularly for breast swelling and ankle swelling. Survey study, 1964 How common are mood and physical changes around menstruation? Very common. One in nine women reported severe pain, irritability or headache, and one in four had moderate to severe premenstrual tension. Psychological symptoms were linked to personality traits related to anxiety. Case report, 1961 What are the main symptoms of premenstrual tension? Premenstrual tension includes mainly anxiety and depression. Some women also have fluid retention, weight gain, and bloating. Most women feel much better once their period starts. Study, 1945 What symptoms do women experience with premenstrual tension? Premenstrual tension causes many different physical and emotional symptoms ranging from mild to severe, including nervousness, irritability, depression, headaches, nausea, and bloating. Show more studies Ask AI about this page Copy prompt ChatGPT ↗ Claude ↗ Perplexity ↗ Google AI Mode ↗ Grok ↗