---
title: Menstrual health trials you could join · Niyora
description: 49 clinical trials on periods, PMS and PMDD that are genuinely open, checked against the registry on 2026-08-20. Not affiliated with any of them.
url: https://niyora.com/research/trials/
---

[Research](https://niyora.com/research/)

# Trials you could actually join

Research on periods only happens if people take part. These are studies on menstrual and premenstrual health that are open right now, pulled from the public ClinicalTrials.gov registry and filtered down to the ones a real person could still sign up for.

Checked against the registry on 2026-08-20.

## Why this list is shorter than the registry says

140

studies the registry returns for these conditions, marked open.

74

of those were due to finish on a date that has already passed.

49

are left once I drop those, plus the 26 that name no location at all.

"Recruiting" on ClinicalTrials.gov means nobody has updated the record, not that the study is still taking people. So I only show studies whose end date has not passed, that someone touched in the last year, and that say where they are. Every card shows its own last-updated date so you can judge for yourself.

## PMS and PMDD

Studies on premenstrual mood, irritability and premenstrual dysphoric disorder.

12 open studies

- Not yet recruiting United Kingdom ### The SPARK-PMDD Study 18 to 42 , women only , looking for about 120 people Run by King's College London [Read the registry entry](https://clinicaltrials.gov/study/NCT07771426) Record last updated 2026-08-18
- Recruiting Turkey (Türkiye) ### THE EFFECT OF GUİDED IMAGERY ON PREMENSTRUAL SYNDROME any age , women only , looking for about 48 people Run by Baskent University [Read the registry entry](https://clinicaltrials.gov/study/NCT07202650) Record last updated 2026-08-12
- Recruiting Pakistan ### Dose-Response Effects of a 6-Week Progressive Resistance Training Program on Premenstrual Syndrome in Adolescent Girls 11 to 19 , women only , looking for about 32 people Run by Riphah International University [Read the registry entry](https://clinicaltrials.gov/study/NCT07754149) Record last updated 2026-08-12
- Recruiting Spain ### Menstrual Cycle Symptoms and Female Health 18 to 45 , women only , looking for about 400 people Run by Universidad Rey Juan Carlos [Read the registry entry](https://clinicaltrials.gov/study/NCT07699224) Record last updated 2026-07-13
- Recruiting United Kingdom ### To Establish Whether Individuals With Premenstrual Dysphoric Disorder (PMDD) Demonstrate a Different Luteal-phase Sex Hormone Profile and Ratio Compared With Asymptomatic Controls. 18 to 45 , women only , looking for about 50 people Run by Lancaster University [Read the registry entry](https://clinicaltrials.gov/study/NCT07686718) Record last updated 2026-07-07
- Recruiting United States ### Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause 18 to 55 , women only , looking for about 20 people Run by Texas Christian University [Read the registry entry](https://clinicaltrials.gov/study/NCT07688720) Record last updated 2026-07-07
- Not yet recruiting Egypt ### Aerobic Exercises Versus Sub Occipital Myofascial Release on Memory Function in Females With Premenstrual Syndrome. 18 to 30 , women only , looking for about 40 people Run by Cairo University [Read the registry entry](https://clinicaltrials.gov/study/NCT07684495) Record last updated 2026-07-06
- Recruiting United States ### CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life 18 to 65 , women only , looking for about 50 people Run by Samphire Group, Inc. [Read the registry entry](https://clinicaltrials.gov/study/NCT07679074) Record last updated 2026-07-01
- Recruiting United States ### Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder 18 to 50 , women only , looking for about 288 people Run by Johns Hopkins University [Read the registry entry](https://clinicaltrials.gov/study/NCT06704594) Record last updated 2026-05-07
- Recruiting United States ### Identification and Validation of Epigenetic Biomarkers of PMDD 18 to 50 , women only , looking for about 500 people Run by Johns Hopkins University [Read the registry entry](https://clinicaltrials.gov/study/NCT06771583) Record last updated 2026-05-07
- Not yet recruiting Canada ### Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder 16 and over , women only , looking for about 72 people Run by St. Joseph's Healthcare Hamilton [Read the registry entry](https://clinicaltrials.gov/study/NCT07554950) Record last updated 2026-04-28
- Not yet recruiting Switzerland ### Microdosing LSD in Women With Premenstrual Disorders 18 to 45 , women only , looking for about 150 people Run by Friederike Holze [Read the registry entry](https://clinicaltrials.gov/study/NCT07189299) Record last updated 2025-09-23

## Period pain

Dysmenorrhea and menstrual cramps. This is where most of the research money goes.

15 open studies

- Not yet recruiting Pakistan ### Diaphragm-Pelvic Floor Synergy Training in Young Females With Primary Dysmenorrhea. 18 to 24 , women only , looking for about 64 people Run by Riphah International University [Read the registry entry](https://clinicaltrials.gov/study/NCT07754305) Record last updated 2026-08-10
- Recruiting Turkey (Türkiye) ### Vibration, Massage, and Myofascial Release in Primary Dysmenorrhea 18 to 30 , women only , looking for about 96 people Run by Istanbul Medipol University Hospital [Read the registry entry](https://clinicaltrials.gov/study/NCT07731243) Record last updated 2026-07-28
- Recruiting United States ### Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD) 18 to 44 , women only , looking for about 24 people Run by University of North Carolina, Chapel Hill [Read the registry entry](https://clinicaltrials.gov/study/NCT07337902) Record last updated 2026-07-14
- Recruiting France ### Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of Dysmenorrhea 18 and over , women only , looking for about 222 people Run by Nantes University Hospital [Read the registry entry](https://clinicaltrials.gov/study/NCT06995287) Record last updated 2026-07-13
- Recruiting Turkey (Türkiye) ### The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea 10 to 19 , women only , looking for about 42 people Run by Acibadem University [Read the registry entry](https://clinicaltrials.gov/study/NCT06398990) Record last updated 2026-07-02
- Recruiting Turkey (Türkiye) ### Connective Tissue Massage and Music-Based Progressive Muscle Relaxation in Primary Dysmenorrhea 18 to 30 , women only , looking for about 36 people Run by Pamukkale University [Read the registry entry](https://clinicaltrials.gov/study/NCT07647276) Record last updated 2026-06-30
- Not yet recruiting Belgium ### Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea 18 to 50 , women only , looking for about 80 people Run by Vrije Universiteit Brussel [Read the registry entry](https://clinicaltrials.gov/study/NCT07645196) Record last updated 2026-06-12
- Not yet recruiting Mexico ### Intervention in Executive Functions and Emotional Self-Regulation in Adolescents With Primary Dysmenorrhea 15 to 18 , women only , looking for about 35 people Run by Universidad Autonoma de Baja California [Read the registry entry](https://clinicaltrials.gov/study/NCT07555886) Record last updated 2026-05-18
- Recruiting Norway ### The Good Pain Consultation in Endometriosis. 16 to 50 , women only , looking for about 110 people Run by Sorlandet Hospital HF [Read the registry entry](https://clinicaltrials.gov/study/NCT07205614) Record last updated 2026-04-28
- Recruiting Spain ### High-Intensity Interval Training and Menstrual Health Experience in Primary Dysmenorrhea. 18 to 40 , women only , looking for about 60 people Run by University of Alcala [Read the registry entry](https://clinicaltrials.gov/study/NCT07391930) Record last updated 2026-04-21
- Not yet recruiting India ### Efficacy of CL25216 on Hormonal Balance and Menstrual Health in Women With Primary Dysmenorrhea. 25 to 40 , women only , looking for about 80 people Run by ApexCPG LLC [Read the registry entry](https://clinicaltrials.gov/study/NCT07529561) Record last updated 2026-04-14
- Not yet recruiting United States ### Vaginal Sildenafil for Primary Dysmenorrhea 18 to 35 , women only , looking for about 50 people Run by Kevin Hellman [Read the registry entry](https://clinicaltrials.gov/study/NCT07508358) Record last updated 2026-04-02
- Not yet recruiting Netherlands ### Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents 12 to 21 , women only , looking for about 874 people Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) [Read the registry entry](https://clinicaltrials.gov/study/NCT07457957) Record last updated 2026-03-09
- Not yet recruiting Egypt ### Impact of Primary Dysmenorrhea on Academic Performance and Quality of Life Among Medical Students at Sohag University 19 to 25 , women only , looking for about 402 people Run by Sohag University [Read the registry entry](https://clinicaltrials.gov/study/NCT07350902) Record last updated 2026-01-20
- Recruiting United States ### A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods). 18 to 35 , women only , looking for about 60 people Run by Azusa Pacific University [Read the registry entry](https://clinicaltrials.gov/study/NCT07209566) Record last updated 2025-10-07

## Other cycle conditions

Endometriosis, PCOS, amenorrhea and general menstrual cycle studies.

22 open studies

- Not yet recruiting Turkey (Türkiye) ### Menstruel Cycle Knowledge Questionnaite 16 to 35 , women only , looking for about 120 people Run by Biruni University [Read the registry entry](https://clinicaltrials.gov/study/NCT07766577) Record last updated 2026-08-17
- Recruiting Nigeria, Pakistan, Tanzania ### Tranexamic Acid for Anaemia Trial 18 and over , women only , looking for about 4000 people Run by London School of Hygiene and Tropical Medicine [Read the registry entry](https://clinicaltrials.gov/study/NCT06519422) Record last updated 2026-08-17
- Recruiting Sweden ### The Impact of the Menstrual Cycle on Physical Exercise and Performance 18 to 35 , women only , looking for about 111 people Run by Karolinska Institutet [Read the registry entry](https://clinicaltrials.gov/study/NCT05697263) Record last updated 2026-08-13
- Recruiting United States ### This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms. 18 to 40 , women only , looking for about 225 people Run by Mila Mend Inc. [Read the registry entry](https://clinicaltrials.gov/study/NCT07764328) Record last updated 2026-08-13
- Recruiting United States ### Body Clocks - Coordination of Peripheral and Central Oscillators 18 to 30 , women only , looking for about 20 people Run by Stanford University [Read the registry entry](https://clinicaltrials.gov/study/NCT07459764) Record last updated 2026-08-12
- Recruiting Brazil ### Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic Pain 18 to 45 , women only , looking for about 64 people Run by Hospital de Clinicas de Porto Alegre [Read the registry entry](https://clinicaltrials.gov/study/NCT07733583) Record last updated 2026-07-29
- Recruiting Ghana, Kenya ### Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management 15 and over , women only , looking for about 100 people Run by University of California, San Francisco [Read the registry entry](https://clinicaltrials.gov/study/NCT05444504) Record last updated 2026-07-14
- Recruiting United States ### Period Pills for Menstrual Regulation: A New Reproductive Health Option 18 and over , women only , looking for about 100 people Run by University of California, San Francisco [Read the registry entry](https://clinicaltrials.gov/study/NCT07671989) Record last updated 2026-06-26
- Recruiting Singapore ### Virtual Menstrual Pain Approaches in Females 16 to 35 , women only , looking for about 145 people Run by Nanyang Technological University [Read the registry entry](https://clinicaltrials.gov/study/NCT07497711) Record last updated 2026-06-23
- Recruiting France ### Understanding Cycles to Improve Women's Health 18 to 39 , women only , looking for about 320 people Run by University Hospital, Montpellier [Read the registry entry](https://clinicaltrials.gov/study/NCT07037082) Record last updated 2026-06-22
- Recruiting United States ### Stress and Menstrual Health 18 to 45 , women only , looking for about 600 people Run by Duke University [Read the registry entry](https://clinicaltrials.gov/study/NCT07566260) Record last updated 2026-06-05
- Recruiting Portugal ### Effects of the Menstrual Cycle and Oral Contraceptive Use on Health and Performance in Athletes 18 to 30 , women only , looking for about 40 people Run by Faculdade de Motricidade Humana [Read the registry entry](https://clinicaltrials.gov/study/NCT07591818) Record last updated 2026-05-18
- Not yet recruiting Canada ### Measurement of Urinary Hormones in Patients With Abnormal Uterine Bleeding to Study Uterine Cancer Progression 35 and over , women only , looking for about 50 people Run by University of British Columbia [Read the registry entry](https://clinicaltrials.gov/study/NCT07581288) Record last updated 2026-05-12
- Recruiting Cameroon, Peru, Switzerland ### Improving Menstrual and VAginal Health for All 18 to 35 , women only , looking for about 100 people Run by Swiss Tropical & Public Health Institute [Read the registry entry](https://clinicaltrials.gov/study/NCT06646185) Record last updated 2026-04-23
- Recruiting Bulgaria, Czechia, Hungary, Italy, Poland, Romania, United Kingdom ### A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis 18 to 44 , women only , looking for about 190 people Run by Gesynta Pharma AB [Read the registry entry](https://clinicaltrials.gov/study/NCT07260669) Record last updated 2026-04-17
- Recruiting United States ### Effera Dose Response: Women's Health 18 to 40 , women only , looking for about 160 people Run by Helaina Inc. [Read the registry entry](https://clinicaltrials.gov/study/NCT07524270) Record last updated 2026-04-13
- Recruiting France ### Impact of Internal Menstrual Protections on Immunity and Vaginal Microbiota 18 to 49 , women only , looking for about 300 people Run by Centre National de la Recherche Scientifique, France [Read the registry entry](https://clinicaltrials.gov/study/NCT07199998) Record last updated 2026-04-09
- Recruiting Hong Kong ### HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine Fibroids 18 to 50 , women only , looking for about 112 people Run by Chinese University of Hong Kong [Read the registry entry](https://clinicaltrials.gov/study/NCT06692335) Record last updated 2026-03-27
- Not yet recruiting Czechia ### Menstrual Cycle and Women's Performance 18 to 35 , women only , looking for about 32 people Run by Charles University, Czech Republic [Read the registry entry](https://clinicaltrials.gov/study/NCT07462286) Record last updated 2026-03-10
- Recruiting Poland, Spain, Switzerland ### Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms 18 and over , women only , looking for about 1000 people Run by Swiss GO Trial Group [Read the registry entry](https://clinicaltrials.gov/study/NCT07397715) Record last updated 2026-02-12
- Not yet recruiting Sweden ### Health and Lifestyle Support for Functional Hypothalamic Amenorrhea 18 to 42 , women only , looking for about 70 people Run by Karolinska Institutet [Read the registry entry](https://clinicaltrials.gov/study/NCT07386223) Record last updated 2026-02-04
- Not yet recruiting United States ### Female Concussion Head Cooling 18 to 27 , women only , looking for about 32 people Run by Penn State University [Read the registry entry](https://clinicaltrials.gov/study/NCT07303933) Record last updated 2025-12-26

## What this is, and what it is not

I am not affiliated with any of these studies, I get nothing if you join one, and none of this is medical advice. It is a directory. Whether a trial is right for you is a conversation with your own doctor, and every study has its own screening process.

The data comes from the ClinicalTrials.gov API, searched on premenstrual syndrome, PMDD, menstrual cycle mood, dysmenorrhea and menstrual health, then deduplicated by registration number. Registry records are maintained by the study teams, not by me, so details can be out of date even when the last-updated stamp is recent. Always check the registry entry before contacting anyone.

Most of what is here is period pain rather than premenstrual mood. That is not a filtering choice, it is what the field is currently studying.

[See what nobody is studying](https://niyora.com/research/gaps/) [The research behind Niyora](https://niyora.com/research/)