---
title: Altered Calcium and Vitamin D in PMDD or Severe PM | PMS & PMDD trial
description: Completed. Clinical trial on Premenstrual Syndrome run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in United States.
url: https://niyora.com/research/trials/altered-calcium-and-vitamin-d-in-pmdd-or-severe-pms-nct00005119/
---

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- Altered Calcium and Vitamin D in PMDD or Severe PMS

Completed

# Altered Calcium and Vitamin D in PMDD or Severe PMS

Altered Calcium And Vitamin D Metabolism in PMDD

Status Completed Registry ID NCT00005119 Type Interventional (tests a treatment) Phase NA Conditions Premenstrual Syndrome What is tested Measures of calcium and bone turnover (procedure) Sponsor National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Where United States Start 2000-05 Completion 2003-10 Last update 2010-03-02

## About the study

Osteoporosis has become one of the most widely recognized disorders of our times affecting an estimated 25 million women in this country. Recent evidence has suggested that premenstrual syndrome (PMS) is associated with a calcium deficiency state and bone loss. This may place premenopausal women at greater risk for osteoporosis. An entity such as PMS may be an important physiological marker of a calcium disturbance. The purpose of this investigation is to understand more completely the extent to which calcium balance is disturbed in severe PMS or Premenstrual Dysphoric Disorder (PMDD) by utilizing new tools to assess calcium and bone turnover. The long term objective is to elucidate the pathophysiology of PMDD or severe PMS as it relates to calcium hormones and bone markers. The experimental design involves the comparison between women witn severe PMS and asymptomatic controls.

Summary from ClinicalTrials.gov.

[See the full record](https://clinicaltrials.gov/study/NCT00005119)

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