---
title: Does Adding Oral Contraceptives to Fluoxetine Impr | PMS & PMDD trial
description: Status unknown. Clinical trial on Premenstrual Syndrome run by Cairo University in Egypt.
url: https://niyora.com/research/trials/does-adding-oral-contraceptives-to-fluoxetine-improve-the-nct02562053/
---

- [Niyora](https://niyora.com/)
- [Research](https://niyora.com/research/)
- [Clinical trials](https://niyora.com/research/trials/)
- Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome?

Status unknown

# Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome?

Does Adding Combined Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome? A Double Blind Placebo Controlled Study.

Status Status unknown Registry ID NCT02562053 Type Interventional (tests a treatment) Phase Phase 3 Conditions Premenstrual Syndrome What is tested Fluoxetine (drug); Combined oral contraceptives (drug); Placebo 1 (drug); Placebo 2 (drug) Sponsor Cairo University Where Egypt Participants 300 (planned) Start 2015-10 Completion 2017-09 Last update 2016-07-06

## About the study

Three hundred women with severe premenstrual syndrome will be divided into 3 groups using computer generated random numbers. Group 1 will receiveCombined oral contraceptives (COC) containing drospirenone (drospirenone 3mg+Ethinylestradiol 0.03mg) daily for 21 days starting from the 3rd day of menstruation in addition to oral fluoxetine 20 mg daily. Group 2 will receive fluoxetine 20 mg daily in addition to an oral placebo similar to COC daily for 21 days starting from the 3rd day of menstruation.Group 3 will receive oral placebo similar to COC daily for 21 days starting from the 3rd day of menstruation in addition to a daily oral placebo similar in size, color and structure to fluoxetine.

Summary from ClinicalTrials.gov.

[See the full record](https://clinicaltrials.gov/study/NCT02562053)

Ask AI about this page

Copy prompt

ChatGPT

↗

Claude

↗

Perplexity

↗

Google AI Mode

↗

Grok

↗