---
title: Effectiveness of Non-hormonal Treatment on Moderat | PMS & PMDD trial
description: Completed. Clinical trial on Premenstrual Syndrome-PMS run by Haleema Sadia in Pakistan.
url: https://niyora.com/research/trials/effectiveness-of-non-hormonal-treatment-on-moderate-to-nct07078708/
---

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- Effectiveness of Non-hormonal Treatment on Moderate to Severe Premenstrual Syndrome

Completed

# Effectiveness of Non-hormonal Treatment on Moderate to Severe Premenstrual Syndrome

Status Completed Registry ID NCT07078708 Type Interventional (tests a treatment) Phase NA Conditions Premenstrual Syndrome-PMS What is tested vitamin D (cholecalciferol) supplementation (dietary_supplement); Placebo (other) Sponsor Haleema Sadia Where Pakistan Participants 100 Start 2024-06-01 Completion 2024-11-30 Last update 2025-07-22

## About the study

A double-blind, randomised, placebo-controlled, parallel trial was conducted involving 100 females aged 18-40, all of whom presented with premenstrual syndrome at the Department of Gynecology and Obstetrics, Avicenna Medical College Hospital, Lahore, Pakistan. Participants were randomly assigned to two groups of equal size: One group received vitamin D supplementation at a dose of 50,000 IU every two weeks along with a daily intake of 1,000 mg of calcium, whereas the comparison group was administered a placebo under the same conditions for 12 weeks. All the participants were examined on premenstrual syndrome with the Premenstrual Symptoms Screening Tool-Adolescent (PSST-A) questionnaire

Summary from ClinicalTrials.gov.

[See the full record](https://clinicaltrials.gov/study/NCT07078708)

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