--- title: PMS and PMDD treatments: what the evidence says | Niyora description: Supplements, medication, therapy and lifestyle changes for PMS and PMDD, rated by the strength of the research. url: https://niyora.com/treatments/ --- - [Niyora](https://niyora.com/) - Treatments 72 treatments guides # PMS and PMDD treatments: what the evidence says Supplements, medicines and therapies for PMS and PMDD, with how strong the evidence is for each. Filter treatments ## Most read Treatments What's in Midol, and does it help PMS? Midol is an over-the-counter brand for period pain and bloating that combines a pain reliever with caffeine or an antihistamine, depending on the formula. It can ease cramps and water retention, but it contains no hormone or mood-acting ingredient, so it doesn't treat PMDD's mood symptoms or ordinary PMS mood changes. Read Treatment Vitex (chasteberry): what it is and whether it helps PMS Vitex (chasteberry) is an herbal extract most consistently shown to help premenstrual breast tenderness; its effect on PMS mood symptoms is weaker and inconsistent across trials, and it hasn't been studied specifically in PMDD. There's no single proven dose, it's generally well tolerated, and a doctor's input matters if you take dopamine-related medication. Read Treatment Evening primrose oil: what it is and whether it helps PMS Evening primrose oil is a seed oil supplement often tried for PMS, hot flashes and breast pain. The best-controlled PMS trials found it worked no better than placebo, though it's shown more promise for breast tenderness. No study has tested it in women with a confirmed PMDD diagnosis. Read Treatment Yaz birth control: what it is and whether it helps PMS Yaz is a combination birth control pill with ethinyl estradiol and drospirenone that stops ovulation. It's approved for contraception, moderate acne, and PMDD in women who also want oral contraception, based on two placebo-controlled trials from the mid-2000s. Read Treatments PMDD treatment: what actually helps First-line PMDD treatment is SSRIs, taken daily or only in the luteal phase, and CBT, both backed by the most consistent trial evidence. Some hormonal options help too, and Vitex agnus-castus has supporting evidence for premenstrual symptoms generally. No herbal or homeopathic remedy outperforms placebo for PMDD itself, and a doctor should guide any medication choice. Read Treatment PMS treatment: what actually helps PMS treatment works best when it's matched to how severe your symptoms are: lifestyle changes and Vitex agnus-castus for mild symptoms, SSRIs or CBT for moderate to severe mood symptoms, and GnRH analogues for severe, treatment-resistant cases. Most options take two to three cycles to show an effect, and tracking daily symptoms is how you know if one is working. Read ## All treatments - [Aerobic exercise for PMDD: what helps and what doesn't→](https://niyora.com/treatments/exercise-for-pmdd/) - [Antidepressants for PMS depression: how SSRIs help→](https://niyora.com/treatments/ssri-for-pms-depression/) - [Birth control for PMDD: does it work?→](https://niyora.com/treatments/birth-control-for-pmdd/) - [Bupropion (Wellbutrin) for PMDD: does it work?→](https://niyora.com/treatments/bupropion-for-pmdd/) - [Calcium supplements for PMDD: do they work?→](https://niyora.com/treatments/calcium-for-pmdd/) - [Calcium supplements for PMS: does it work?→](https://niyora.com/treatments/calcium-for-pms/) - [Can birth control help PMS?→](https://niyora.com/treatments/birth-control-for-pms/) - [Can men take Midol?→](https://niyora.com/treatments/can-men-take-midol/) - [Can Midol make you sleepy? Side effects, including mood→](https://niyora.com/treatments/midol-side-effects/) - [Chasteberry tea (vitex): benefits and how to make it→](https://niyora.com/treatments/vitex-tea/) - [Diet for food cravings during your period→](https://niyora.com/treatments/diet-for-cravings-during-period/) - [Diet for PMDD: what actually helps→](https://niyora.com/treatments/pmdd-diet/) - [Diet for PMS food cravings before your period→](https://niyora.com/treatments/diet-for-cravings-before-period/) - [Escitalopram (Lexapro) for PMDD: does it work?→](https://niyora.com/treatments/escitalopram-for-pmdd/) - [Essential oils for PMS mood swings→](https://niyora.com/treatments/essential-oils-for-pms-mood-swings/) - [Essential oils for PMS: does it work?→](https://niyora.com/treatments/essential-oils-for-pms/) - [Evening primrose oil 1000 mg: dosage, timing, and benefits→](https://niyora.com/treatments/evening-primrose-oil-dosage/) - [Evening primrose oil for perimenopause mood: does it work?→](https://niyora.com/treatments/evening-primrose-oil-for-perimenopause-mood/) - [Evening primrose oil for PMS: does it work?→](https://niyora.com/treatments/evening-primrose-oil-for-pms/) - [Evening primrose oil side effects, including mood→](https://niyora.com/treatments/evening-primrose-oil-side-effects/) - [Excedrin for PMS: does it work?→](https://niyora.com/treatments/excedrin-for-pms/) - [Fluoxetine (Prozac) for PMDD: does it work?→](https://niyora.com/treatments/fluoxetine-for-pmdd/) - [Fluoxetine (Prozac) for PMS: does it work?→](https://niyora.com/treatments/fluoxetine-for-pms/) - [Generic Yaz: names and differences→](https://niyora.com/treatments/generic-yaz/) - [How long does Midol take to work?→](https://niyora.com/treatments/how-long-does-midol-take-to-work/) - [How often to take Pepcid AC and antihistamines for PMDD→](https://niyora.com/treatments/antihistamines-dosage/) - [How to help PMDD: what actually helps→](https://niyora.com/treatments/how-to-manage-pmdd/) - [How to relieve breast pain before your period→](https://niyora.com/treatments/treatment-for-breast-tenderness-before-period/) - [How to relieve PMS pain before your period→](https://niyora.com/treatments/treatment-for-aches-and-pains-before-period/) - [HRT for PMDD: does it work?→](https://niyora.com/treatments/hrt-for-pmdd/) - [Ibuprofen dosage: how much and when→](https://niyora.com/treatments/ibuprofen-dosage/) - [Ibuprofen for PMS: does it work?→](https://niyora.com/treatments/ibuprofen-for-pms/) - [Iron supplements for PMS: do they work?→](https://niyora.com/treatments/iron-for-pms/) - [IUDs for PMS: does it work?→](https://niyora.com/treatments/iud-for-pms/) - [Lamictal for PMDD: does it work?→](https://niyora.com/treatments/lamotrigine-for-pmdd/) - [Magnesium for PMDD: does it work?→](https://niyora.com/treatments/magnesium-for-pmdd/) - [Magnesium supplement for PMS: does it work?→](https://niyora.com/treatments/magnesium-for-pms/) - [Medication for bloating before your period→](https://niyora.com/treatments/medicine-for-bloating-before-period/) - [Medicine for PMS cramps before your period→](https://niyora.com/treatments/medicine-for-cramps-before-period/) - [Midol Complete: what's in it and what it does→](https://niyora.com/treatments/midol-complete/) - [Midol dosage: can you take it on an empty stomach?→](https://niyora.com/treatments/midol-dosage/) - [Midol for PMS: does it work?→](https://niyora.com/treatments/midol-for-pms/) - [Mood swings on Nexplanon: what the evidence shows→](https://niyora.com/treatments/nexplanon-and-mood/) - [Moodiness with Mirena and other IUDs: what the evidence shows→](https://niyora.com/treatments/iud-and-mood/) - [Natural remedies for PMS: what actually helps→](https://niyora.com/treatments/natural-remedies-for-pms/) - [Pepcid and antihistamines for PMDD: does it work?→](https://niyora.com/treatments/antihistamines-for-pmdd/) - [Pepcid and antihistamines for PMS: does it work?→](https://niyora.com/treatments/antihistamines-for-pms/) - [Perimenopause mood swing treatment: what actually helps→](https://niyora.com/treatments/perimenopause-mood-swings-treatment/) - [PMDD medications: what actually helps→](https://niyora.com/treatments/pmdd-medication/) - [PMDD natural supplements: what actually helps→](https://niyora.com/treatments/natural-remedies-for-pmdd/) - [PMS bloating treatment: what helps→](https://niyora.com/treatments/treatment-for-bloating-before-period/) - [PMS diet: what actually helps→](https://niyora.com/treatments/pms-diet/) - [Progesterone supplements for a short luteal phase: do they help PMS?→](https://niyora.com/treatments/progesterone-for-pms/) - [Sertraline (Zoloft) for PMDD: does it work?→](https://niyora.com/treatments/sertraline-for-pmdd/) - [Slynd for PMDD: does it work?→](https://niyora.com/treatments/slynd-for-pmdd/) - [SSRIs for PMDD: does it work?→](https://niyora.com/treatments/ssri-for-pmdd/) - [SSRIs for PMDD: how they work, and what to expect→](https://niyora.com/treatments/ssris-for-pmdd/) - [Supplements for PMDD: what actually helps→](https://niyora.com/treatments/supplements-for-pmdd/) - [Vitamin B6 for PMS: does it work?→](https://niyora.com/treatments/vitamin-b6-for-pms/) - [Vitex (chasteberry) for PMDD: does it work?→](https://niyora.com/treatments/vitex-for-pmdd/) - [Vitex (chasteberry) side effects, including mood changes→](https://niyora.com/treatments/vitex-side-effects/) - [Why do you eat so much before your period?→](https://niyora.com/treatments/diet-for-hunger-before-period/) - [Yaz for PMDD: does it work?→](https://niyora.com/treatments/yaz-for-pmdd/) - [Yaz side effects, including mood→](https://niyora.com/treatments/yaz-side-effects/) - [Yaz vs Yasmin: the differences that matter for PMS and PMDD→](https://niyora.com/treatments/yaz-vs-yasmin/) - [Yoga poses for PMS cramps: what works→](https://niyora.com/treatments/yoga-for-pms-cramps/) No match. 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