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Survey study, 1975

Does menstruation cause extreme sleepiness?

One girl had severe sleepiness linked to her periods, sleeping about 14 hours a day during episodes. The cause is unclear, but hormones may play a role.

Early or limited evidence One 13-year-old girl with extreme sleepiness linked to her menstrual cycle.

What they did

They observed a 13-year-old girl who had repeated episodes of extreme sleepiness occurring with each menstrual cycle. They measured how much she slept during episodes and tested her ability to concentrate and her brain chemistry.

What they found

During sleepy episodes, she slept an average of 14 hours and 19 minutes per 24 hours. Her ability to do mental tasks was significantly impaired. Tests showed an abnormal increase in a brain chemical (5-hydroxyindolacetic acid), suggesting changes in serotonin activity. Hormone tests did not show major abnormalities. Because the sleepiness was closely linked to her menstrual cycle, her doctors suspected progesterone involvement and started hormonal treatment, which appeared to help.

What it means for you

This is one rare case of extreme sleepiness linked to menstruation. The cause remains unknown, and we cannot know from a single case whether hormonal treatment truly helps or how common this condition is. More study of other women would be needed.

13 years old

Age of girl

14 hours 19 min

Sleep during episodes per day

About the study

Original title
A menstruation-linked periodic hypersomnia. Kleine-Levin syndrome or new clinical entity?
Authors
Billiard M, Guilleminault C, Dement WC
Journal
Neurology
Year
1975
Study design
Survey study
What was tested
Hormonal treatment was started based on clinical observation.

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