Non-randomised trial, 2022
Does a topical gel help acne around your period?
Yes, the combination gel improved period-related acne in all 22 women with no serious side effects. The study was very small with no comparison group.
What they did
A pilot study where 22 adult women with period acne applied a combination gel daily for 99 days. Doctors measured improvement every 14 days using a standard acne scoring system.
What they found
There was significant improvement in acne scores and the number of acne lesions. All 22 women tolerated the medication well with no serious adverse effects.
What it means for you
This topical gel might be a good option for period acne instead of hormonal birth control. Main limitation: very small sample and no comparison group, so larger studies are needed to confirm it works.
22
women
99 days
treatment duration
daily
application frequency
About the study
- Original title
- A Pilot Study of Clindamycin Phosphate 1.2% and Benzoyl Peroxide 3.75% Combination Gel in the Treatment of Perimenstrual Acne
- Authors
- Marushchak O, Gagliotti M, Vekaria AS et al.
- Journal
- The Journal of clinical and aesthetic dermatology
- Year
- 2022
- Study design
- Non-randomised trial
- Participants
- 22
- What was tested
- Clindamycin phosphate 1.2% and benzoyl peroxide 3.75% combination gel
- Open access
- Yes
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/36381180/