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Non-randomised trial, 1982

Does your menstrual cycle affect how your brain works and how well you do on mental tasks?

Yes, brain activity and task performance change across the cycle, with performance best around ovulation and worst in the late luteal phase. Oral contraceptives eliminate these changes. This is a very small study with no control group.

Early or limited evidence 14 women

What they did

14 women had their brain electrical activity measured with EEG, hormone levels tested, and took performance tests during their natural cycle and again while on oral contraceptives.

What they found

Brain waves were slower during the follicular phase and faster during the luteal phase. Performance on tasks was best around ovulation and worst during the late luteal and early menstrual phases. When women took oral contraceptives, these cycle-related performance changes did not happen. Changes in brain activity matched changes in hormone levels.

What it means for you

Your menstrual cycle affects how your brain works electrically and how well you think, likely through hormone effects on brain chemistry. Oral contraceptives can prevent these monthly performance swings. The main limitation is the very small sample size and lack of randomization.

14

women studied

slower waves

in follicular phase

around ovulation

best performance

About the study

Original title
Changes in physiological, EEG and psychological parameters in women during the spontaneous menstrual cycle and following oral contraceptives
Authors
Becker D, Creutzfeldt OD, Schwibbe M et al.
Journal
Psychoneuroendocrinology
Year
1982
Study design
Non-randomised trial
Participants
14
What was tested
Oral contraceptives versus natural menstrual cycle

Topics