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Survey study, 2011

Do women with PMDD have higher cholesterol levels?

Women with PMDD had higher average cholesterol (180.82 mg/dL) than women without PMDD (162.45 mg/dL). About 24% of women with PMDD had high cholesterol versus none of the controls. However, the sample was very small.

Early or limited evidence 34 women with PMDD and 20 women without PMDD

What they did

Researchers measured premenstrual serum cholesterol levels in 34 women with PMDD and 20 women without PMDD.

What they found

The PMDD group had a mean cholesterol of 180.82 +/- 34.47 mg/dL versus 162.45 +/- 21.29 mg/dL in controls (p=0.036). High cholesterol above 200 mg/dL was found in 23.53% (8 out of 34) of the PMDD group and 0% of controls (p=0.019).

What it means for you

Higher cholesterol in PMDD may suggest a link between PMDD and anxiety-like disorders. However, the sample was very small, so this finding may not be reliable. The study did not account for diet, medications, or other factors that affect cholesterol, so we cannot be sure the difference comes from PMDD.

180.82

Mean cholesterol in PMDD group (mg/dL)

162.45

Mean cholesterol in controls (mg/dL)

23.53%

High cholesterol in PMDD group

About the study

Original title
Elevated serum cholesterol levels in women with premenstrual dysphoric disorder
Authors
Hsiao MC, Liu CY, Hsu SC et al.
Journal
International journal of psychiatry in medicine
Year
2011
Study design
Survey study
Participants
34
What was tested
Measurement of premenstrual serum cholesterol levels

Topics