Randomised trial, 2026
Does vitamin D help with PMS symptoms?
This review found that low vitamin D is linked to more severe PMS symptoms, and supplementation significantly reduces PMS scores, especially for mood-related symptoms. However, the studies used different doses and measuring methods, so more rigorous research with standardized dosing is needed.
What they did
Narrative review of studies published 2013-2025 examining vitamin D's role in female reproductive health and various disorders. Synthesized evidence on how vitamin D affects reproductive conditions including PMS. Reviewed mechanisms through which vitamin D receptors in reproductive organs influence hormones and immunity.
What they found
Low vitamin D status correlates with more severe PMS symptoms. Supplementation significantly reduces total PMS scores, particularly improving mood-related domains. The review also discusses effects on other conditions (PCOS, endometriosis, pregnancy outcomes) but notes that studies used different doses and measurement methods. The overall evidence is limited by heterogeneous study designs and variable dosing approaches.
What it means for you
Low vitamin D may contribute to worse PMS symptoms, and supplementation might help reduce them. However, studies reviewed used different doses, durations, and ways of measuring vitamin D, and no specific improvement percentages were reported. Larger, more rigorous studies with standardized dosing are needed to establish clear clinical guidelines.
2013-2025
years of studies reviewed
significant
PMS score reduction with vitamin D
mood domains
greatest improvement area
About the study
- Original title
- Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications
- Authors
- Alsuwaidi A, AlAnouti F, Papandreou D
- Journal
- Women's health (London, England)
- Year
- 2026
- Study design
- Randomised trial
- What was tested
- Narrative review of vitamin D supplementation studies (doses and durations varied)
- Open access
- Yes
- Read the paper
- doi.org/10.1177/17455057261446942
Topics
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