Case-control study, 2025
Do women with rheumatoid arthritis have more PMDD?
Yes. Women with rheumatoid arthritis are 4.54 times more likely to have PMDD (24% vs 6%) and 4.9 times more likely to experience functional impairment from PMDD compared to healthy women.
What they did
Cross-sectional study comparing 67 women with rheumatoid arthritis to 67 healthy women in Mexico, matched by age (mean 39.8 years). Used a screening tool to assess for PMDD and its impact on daily functioning.
What they found
PMDD was present in 24% of RA patients (15 women) versus 6% of controls (4 women). Functional impairment from PMDD was more common in RA patients (28.4%, 19 women) than controls (7.5%, 4 women). Women with RA had 4.54 times higher odds of PMDD and 4.9 times higher odds of functional impairment.
What it means for you
The inflammation from rheumatoid arthritis may increase PMDD risk or severity. This is one study from one center in Mexico, so results may not apply to all populations. More research is needed.
24%
PMDD in RA women vs 6% controls
4.54
Odds ratio for PMDD
28.4%
Functional impairment in RA
About the study
- Original title
- Evaluating Premenstrual Dysphoric Disorder in Women With Rheumatoid Arthritis and Healthy Female Subjects
- Authors
- Bardan-Inchaustegui AC, Colunga-Pedraza IJ, Elizondo-Benitez MF et al.
- Journal
- Musculoskeletal care
- Year
- 2025
- Study design
- Case-control study
- Participants
- 19
- What was tested
- None - observational study
- Open access
- Yes
- Read the paper
- doi.org/10.1002/msc.70106
Topics
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