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Survey study, 2025

Do women with PMS have thinking problems that change with the menstrual cycle or persist all month?

Women with PMS had lasting problems with working memory and impulse control across the entire menstrual cycle, not just before their period. These problems correlated with symptom severity but not with hormone levels.

Moderate study design 105 women aged 19-35, including 54 with PMS or PMDD and 51 controls

What they did

Cross-sectional study of 105 women aged 19-35, with 54 having PMS or PMDD and 51 as controls. Women were tested three times across their menstrual cycle (mid-follicular, mid-luteal, and late luteal phases) using computerized tasks to measure working memory and impulse control. Hormone levels were measured from saliva samples, and menstrual symptoms were tracked across two cycles.

What they found

Women with PMS/PMDD showed working memory deficits under high cognitive load across all cycle phases. They also had longer stop signal reaction times (slower impulse control) across all cycle phases, and these reaction times correlated with premenstrual symptom severity. There was no significant correlation between cognitive performance and gonadal hormone levels.

What it means for you

Thinking problems in PMS may not be caused by hormone fluctuations but may be a lasting trait of the condition that affects the entire month. This could help explain why women with PMS have difficulty managing emotions and behavior. The study tested only two types of thinking skills.

105

Women tested

54

With PMS or PMDD

3

Menstrual cycle phases tested

About the study

Original title
Persistent Impairment of Executive Functions in Premenstrual Syndrome: Cause or Effect?
Authors
Gnaiger AM, Werlein P, Gruschwitz P et al.
Journal
PsyArXiv
Year
2025
Study design
Survey study
Participants
105
What was tested
None

Topics