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Cohort study, 2026

Does psychological distress explain why PMS reduces well-being?

Possibly. Psychological distress accounted for 78.7% of the connection between PMS and reduced well-being in adolescent girls. However, this cross-sectional study cannot prove cause and effect.

Early or limited evidence 350 adolescent girls aged 13-17 from private schools in Bangalore, India

What they did

Researchers studied 350 adolescent girls aged 13-17 from private schools in Bangalore, India. They measured PMS screening status using a standardized tool, and assessed psychological distress and well-being using validated questionnaires.

What they found

Girls with PMS screening positive status had more psychological distress and lower well-being. Psychological distress explained 78.7% of the connection between PMS status and reduced well-being. The model explained 23.0% of the overall variation in well-being.

What it means for you

The study suggests psychological distress may be an important link between PMS and lower well-being in adolescent girls. However, because the study measured everyone at one point in time, it cannot prove that distress causes lower well-being.

350

girls in study

78.7%

of association through distress

23.0%

of variance in well-being explained

About the study

Original title
Premenstrual Syndrome and Psychological Well-Being Among Adolescent Girls: The Indirect Role of Psychological Distress in a Cross-Sectional Study
Authors
Keziah Mary Sam, Hementhakumara V
Journal
Journal of Health and Rehabilitation Sciences
Year
2026
Study design
Cohort study
Participants
350
What was tested
None; this was an observational study
Open access
Yes
Original abstract

Introduction: Premenstrual syndrome (PMS) is associated with psychological distress and reduced well-being among adolescent girls. However, the extent to which distress statistically accounts for the association between PMS screening status and eudaimonic psychological well-being remains insufficiently examined in Indian adolescents. Aim: To examine whether psychological distress is associated with the indirect statistical pathway linking PMS screening status with psychological well-being among adolescent girls in Bangalore, India. Methods: A cross-sectional study included 350 adolescent girls aged 13–17 years from private schools in Bangalore. PMS screening status was assessed using the PSST-A, while psychological distress and well-being were measured using the DASS-Y and PWBS-SDCP, respectively. A bootstrapped path-analytic indirect-association model was estimated using lavaan in R with 5,000 resamples and bias-corrected 95% confidence intervals. Results: PMS screening status was positively associated with distress (rpb = .46, p < .001) and negatively associated with well-being (rpb = −.26, p < .001). The indirect association through distress was significant (β = −.21, B = −10.46, 95% CI [−13.98, −7.57], p < .001), accounting for 78.7% of the total association. The direct association was not significant (β = −.06, B = −2.82, p = .291). The model explained 23.0% of the variance in well-being. Conclusions: Psychological distress statistically accounted for a substantial proportion of the cross-sectional association between PMS screening status and well-being. Given the cross-sectional design, these findings indicate a statistical indirect association rather than a temporal or causal mediation mechanism and should inform future longitudinal research.

Reproduced under CC-BY.

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