Skip to content

Cohort study, 2025

What causes migraine in female college students who have PMS?

Among college students with PMS, those with migraine have worse sleep quality and higher anxiety. Poor sleep and anxiety appear to predict migraine risk.

Moderate study design 3,131 female college students with PMS in northeastern Sichuan Province, China

What they did

Cross-sectional study of 3,131 female college students across nine universities in northeastern Sichuan, China. Researchers screened for PMS using the Premenstrual Symptoms Screening Tool and for migraine using the ID-Migraine questionnaire. They also measured depression, anxiety, stress, sleep quality, and phone addiction using standard questionnaires.

What they found

18.8% of students with PMS also had migraine. Students with both conditions had significantly worse sleep quality and higher depression, anxiety, and stress compared to those with PMS alone. Logistic regression analysis showed that decreased sleep quality (odds ratio 1.08) and anxiety (odds ratio 1.24) were significant independent risk factors for migraine in this group.

What it means for you

If you have PMS and migraine, improving sleep quality and managing anxiety might help reduce migraine risk. The study is limited to college students in one region of China, so findings may not apply to all women with PMS. The study is cross-sectional, so we cannot determine whether poor sleep and anxiety cause migraine or result from it.

18.8%

Migraine prevalence in PMS group

1.08

Sleep quality odds ratio for migraine

1.24

Anxiety odds ratio for migraine

About the study

Original title
Prevalence and associated factors of migraine among female college students with premenstrual syndrome
Authors
He M, Liu L, Wang S et al.
Journal
Scientific reports
Year
2025
Study design
Cohort study
Participants
3,131
What was tested
None
Open access
Yes

Topics