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Cohort study, 2002

How common is PMDD and does it stick around?

PMDD affects 5.8% of young women and tends to persist. Most women with PMDD also have anxiety or other mental health conditions, use healthcare more, and have higher suicide rates.

Moderate study design 1488 women aged 14-24, 1251 at follow-up, from community sample

What they did

Researchers followed 1488 women aged 14-24 for 48 months (1251 completed follow-up), using diagnostic interviews to check for PMDD and other mental disorders.

What they found

5.8% had PMDD at baseline, 5.3% when depression cases were excluded. An additional 18.6% had near-threshold PMDD. Only 7.4% had PMDD at any point during lifetime follow-up. PMDD was stable with less than 10% remission. Comorbidity was high: 47.4% also had anxiety disorders, 22.9% mood disorders, 28.4% somatoform disorders. Only 26.5% had no other mental disorder. High rates of nicotine dependence and PTSD. Women with PMDD had more impairment days, higher healthcare use, and more suicide attempts.

What it means for you

PMDD is real and moderately common in young women, tends to persist, and usually comes with other mental health issues. Women with PMDD have higher suicide risk. A key limitation is that the study did not use daily symptom ratings, which standard diagnostic criteria require.

5.8%

prevalence of PMDD at baseline

47.4%

also have anxiety disorders

7.4%

lifetime incidence

About the study

Original title
Prevalence, incidence and stability of premenstrual dysphoric disorder in the community
Authors
Wittchen H -U, Becker E, Lieb R et al.
Journal
Psychological medicine
Year
2002
Study design
Cohort study
Participants
1,251
What was tested
None
Open access
Yes

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