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Cohort study, 2008

Do women with autism have PMS more often than women without autism?

Yes, women with autism had much higher rates of PMS compared to women without autism. In the autism group, 92% showed PMS symptoms, while only 11% of the control group did.

Moderate study design 26 women with autism and learning disability, 36 women with learning disability alone

What they did

Researchers compared 26 women with autism and learning disability to 36 women with learning disability alone (matched for age, living situation, intelligence, marital status, number of children, behaviour problems, and ethnicity). Researchers watched for daily PMS symptoms over 3 consecutive menstrual cycles.

What they found

92% of women with autism met the diagnosis criteria for PMS based on a 30% or greater increase in symptoms in the luteal phase (the two weeks before the period). Only 11% of the control group met the criteria. This difference was highly statistically significant.

What it means for you

Women with autism are much more likely to have PMS than women without autism. This finding suggests that autism and menstrual cycle changes may be connected in some way. However, the study was small and limited to women with learning disability, so the findings may not apply to all women with autism.

92%

women with autism who met PMS criteria

11%

women without autism who met criteria

3

menstrual cycles observed

About the study

Original title
Prevalence of premenstrual syndrome in autism: a prospective observer-rated study
Authors
Obaydi H, Puri BK
Journal
The Journal of international medical research
Year
2008
Study design
Cohort study
Participants
36
What was tested
No intervention; this was an observational study
Open access
Yes

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