Review, 1985

Do prostaglandin inhibitor drugs help with menstrual symptoms?

Yes, prostaglandin inhibitor drugs such as NSAIDs like ibuprofen significantly reduce menstrual symptoms in many women, with rapid relief and few side effects.

Early or limited evidence People with menstrual symptoms (specific sample sizes not stated)

What they did

A literature review of studies using prostaglandin inhibitor drugs (anti-inflammatory medications like NSAIDs) for treating menstrual symptoms.

What they found

Prostaglandin inhibitors had substantial efficacy for treating menstrual symptoms. Many patients experienced relief of multiple symptoms. Treatment is simple with rapid relief. Side effects are mild and uncommon. No serious complications were reported with short-term dosage regimens.

What it means for you

NSAIDs like ibuprofen appear to be safe and effective treatment for menstrual symptoms including cramps and period pain. This is practical and accessible treatment. The main limit is that this is a review, not a specific study, and focuses on short-term use.

About the study

Original title: Prostaglandin inhibitors in gynaecology
Authors: Fraser IS
Journal: The Australian & New Zealand journal of obstetrics & gynaecology
Year: 1985
Study design: Review
What was tested: Prostaglandin inhibitor drugs (NSAIDs)
Read the paper: doi.org/10.1111/j.1479-828x.1985.tb00621.x

Topics

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