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Study, 2011

Can sensitivity to your own hormones cause PMS?

Yes. Some women may have unusual sensitivity to estrogen and progesterone that causes PMS and other problems. This can be diagnosed with skin tests and treated with small hormone doses.

Early or limited evidence Not applicable - clinical overview, not a study

What they did

This is a clinical explanation of hormone sensitivity, not a research study with specific participants.

What they found

Hypersensitivity to estrogens and progestogens can cause premenstrual syndrome, painful periods, and fertility problems. Diagnosis is confirmed by skin testing for inflammatory responses to small hormone doses. Treatment involves desensitization with small hormone doses.

What it means for you

If you have PMS, one possible cause could be hormone sensitivity. A skin test could diagnose it. However, this is a clinical opinion, not evidence from a research study.

About the study

Original title
Steroid hormone hypersensitivity: clinical presentation and management
Authors
Itsekson AM, Seidman DS, Zolti M et al.
Journal
Fertility and sterility
Year
2011
Study design
Study
What was tested
Hormone desensitization therapy
Open access
Yes

Topics