Study, 1990
Could how progesterone receptors work explain PMS?
Researchers proposed that PMS might be caused by how progesterone receptors transport progesterone into cells. This could explain why blood tests for progesterone don't help diagnose PMS and why high doses are needed for treatment.
Early or limited evidence No people studied - this is a theoretical paper based on molecular biology research
What they did
This was not a study with people. Instead, researchers looked at recent discoveries about how progesterone receptors work and proposed a theory about what might cause PMS.
What they found
They suggest PMS relates to how progesterone receptors transport progesterone into cells during the reproductive years.
What it means for you
This is a theory, not proven by testing in women. It is an idea from cell biology research that could help explain why PMS happens and why some treatments fail. It has not been tested in people yet.
About the study
- Original title
- The aetiology of premenstrual syndrome is with the progesterone receptors
- Authors
- Dalton K
- Journal
- Medical hypotheses
- Year
- 1990
- Study design
- Study
- What was tested
- None - theoretical paper
- Read the paper
- doi.org/10.1016/0306-9877(90)90026-b