Randomised trial, 2009
Does vitamin B6 (pyridoxine) help with premenstrual syndrome symptoms?
This question cannot be answered here: the title refers to a trial of vitamin B6 for PMS, but the abstract text supplied is actually about the chemistry of breaking down dextran (a sugar polymer) using ultrasound, with no mention of vitamin B6, PMS or any women at all.
What they did
The abstract describes a lab chemistry experiment: six dextran samples of different starting molecular weights were broken down using ultrasound, and their molecular weight was tracked over time with a lab technique (HPGPC). This is not a study of people, vitamin B6 or PMS.
What they found
As ultrasonic treatment continued, the dextran samples' average molecular weight and spread of molecular weights (polydispersity) decreased. Higher starting molecular weight samples broke down more, especially early on. A mathematical model (Malhotra model) fit the molecular weight data well, and a 'midpoint scission' model best matched how the dextran chains broke, with a strong statistical fit (R2 > 0.99).
What it means for you
Because the abstract text does not match its title, there is no usable information here about vitamin B6 or PMS. This looks like a data mix-up, so no practical takeaway for PMS can be drawn from it.
6
dextran samples tested
>0.99
model fit (R2)
About the study
- Original title
- The Evaluation of the Effectiveness of Pyridoxine (Vitamin B6) for the Treatment of Premenstrual Syndrome: A Double Blind Randomized Clinical Trial
- Authors
- Maryam Kashanian, Maryam Kashanian, Robabeh Mazinani et al.
- Journal
- Journal of Nutrition Education and Behavior
- Year
- 2009
- Study design
- Randomised trial
- What was tested
- None relevant to PMS; the abstract describes ultrasonic treatment of dextran in a lab
- Read the paper
- doi.org/10.1016/j.jneb.2009.03.006
Topics
Related studies
Systematic review, 2025
Do nutritional interventions help with emotional symptoms of PMS?
Systematic review, 2013
Does Vitex (chaste tree) help PMS and PMDD symptoms?
Review, 2011
What are PMS and PMDD, and how common are they?
Systematic review, 2009
Which herbs, vitamins and minerals help treat PMS?
Systematic review, 2007
What treatments work for premenstrual syndrome?
Randomised trial, 2003
What complementary and alternative medicines help with women's reproductive health issues?