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Study, 2021

Does ulipristal acetate help women with PMDD?

Yes. Women taking ulipristal acetate experienced improvement in irritability and depression, and half of the women achieved complete remission of PMDD.

Strong study design Women with PMDD in a placebo-controlled trial

What they did

Women with PMDD received either ulipristal acetate or placebo in a controlled trial. Researchers measured whether irritability and depression symptoms improved.

What they found

Women taking ulipristal acetate experienced improvement in irritability and depression symptoms. Half of the women taking the medication achieved full remission of PMDD symptoms.

What it means for you

Ulipristal acetate appears to be an effective treatment for PMDD, helping women reduce irritability and depression with some women achieving complete remission. This is a placebo-controlled trial design, which is a strong way to test whether a treatment actually works.

50%

Women who achieved full remission

About the study

Original title
Ulipristal acetate shows promise for treatment of PMDD
Journal
The Brown University Psychopharmacology Update
Year
2021
Study design
Study
What was tested
Ulipristal acetate versus placebo

Topics