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Study, 1980

Do the hormones oxytocin and vasopressin change during the menstrual cycle?

In most women these hormones showed no clear change across the cycle. In one woman with PMS symptoms, vasopressin levels were significantly higher after ovulation than before.

Early or limited evidence 3 women, one with typical PMS symptoms.

What they did

3 women collected 24-hour urine samples at different points in their menstrual cycle. The levels of two hormones, oxytocin and vasopressin, were measured in each sample.

What they found

Two women showed no change in either hormone across cycle phases. One woman with PMS symptoms and a weight gain of 1.5 kg showed significantly higher vasopressin levels after ovulation (39.45 ng/24 h) compared to before ovulation (25.3 ng/24 h).

What it means for you

These hormones do not clearly change through the cycle in most women studied. Only one woman with PMS symptoms showed a change. This study is very small with only 3 women, so firm conclusions cannot be drawn.

3

Women studied

1.5 kg

Weight gain in PMS woman

39.45 ng/24 h

Vasopressin after ovulation

About the study

Original title
[Urinary elimination of oxytocin and vasopressin measured by radioimmunoassay in different phases of the menstrual cycle in women]
Authors
Geelen G, Allevard AM, Jarsaillon E et al.
Journal
Comptes rendus des seances de la Societe de biologie et de ses filiales
Year
1980
Study design
Study
Participants
3

Topics