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Study, 1992

Do estrogen patches help with menopausal symptoms?

In this small study, 75% of women showed improvement in menopausal symptoms after 9 weeks of treatment with estrogen patches.

Early or limited evidence 33 women aged 30 to 65

What they did

33 women aged 30 to 65 received estrogen patches (Estraderm TTS-50) containing 0.004 grams of estradiol. The patches were worn for 3 weeks each month, for 9 weeks total. Researchers measured symptoms before, during, and after treatment using a standard symptom scale and blood hormone tests.

What they found

After 9 weeks, 75% of women showed improvement in symptoms. The symptom score decreased, and estradiol levels increased in their blood.

What it means for you

Estrogen patches may help some women with menopausal symptoms. However, this was a small study with no control group to compare to, so we cannot be sure the improvement came from the patches or from other causes.

33

women in the study

75%

showed improvement

9 weeks

total duration of treatment

About the study

Original title
[Use of estrogens in skin patches in treatment of pre-menstrual syndrome]
Authors
Liber Z, Spiewankiewicz B, Stelmachów J
Journal
Polski tygodnik lekarski (Warsaw, Poland : 1960)
Year
1992
Study design
Study
Participants
33
What was tested
Estraderm TTS-50 patches containing 0.004 grams of 17-estradiol, worn for 3 weeks each month for 9 weeks total

Topics