Skip to content

Systematic review, 2025

What are the main trends in research about premenstrual disorders and related conditions?

Research on premenstrual disorders has grown steadily from 1999 to 2023. Most research comes from North America. Scientists are increasingly studying connections between PMDD and bipolar disorder.

Moderate study design Published research papers on premenstrual disorders from 1999 to 2023 (149 papers analyzed)

What they did

The researchers analyzed 149 published scientific papers about premenstrual disorders and conditions that occur together with them from 1999 to 2023. They used software tools to examine publication patterns by country, institution, journal, author, and research topic.

What they found

The number of publications grew from 1999 to 2023. The US and Canada published the most research. McMaster University and Harvard University produced the most influential work. Frey BN from McMaster University was the most prolific author. The American Journal of Psychiatry was the most-cited journal (impact factor 17.7). Research shifted over time from counting how many people have these conditions to studying how the conditions develop and how to diagnose them. The connection between PMDD and bipolar disorder emerged as a rising research focus.

What it means for you

This study tracks what scientists are researching, not whether treatments work. Scientists are paying more attention to premenstrual disorders, especially in North America. The growing focus on the connection between PMDD and bipolar disorder suggests this is an important area to study further.

149

Published papers analyzed

1999-2023

Time period covered

17.7

Impact factor of most-cited journal

About the study

Original title
A global perspective: Trends and insights in premenstrual disorder comorbidity research by bibliometric analysis (1999-2023)
Authors
Cheng X, Li H, Gao M et al.
Journal
Medicine
Year
2025
Study design
Systematic review
What was tested
Not applicable - this is a study of research trends
Open access
Yes
Original abstract

Background: Premenstrual disorders represent a constellation of incapacitating gynecological disorders with numerous coexisting conditions. The identification and comprehension of disease-related comorbidities are of paramount importance in the medical field. This study aims to systematically review existing research and identify potential focus areas through bibliometric analysis. Methods: One hundred forty-nine publications on comorbidity in psychotic mood disorders between 1999 and 2023 were retrieved from the Web of Science Core Collection. The data was analyzed using bibliometric tools such as CiteSpace 6.1.R2 and VOSviewer. Specifically, the study examined the annual publication count, contributions by country and institution and details on journals, authors, citation counts, and keywords. Results: The data were retrieved on August 3, 2023. The annual number of publications showed an upward trend from 1999 to 2023. Globally, the US and Canada presented the highest publication counts and served as core research regions. Meanwhile, McMaster University and Harward University exhibited the highest output and influence by institution. In terms of author, Frey BN (McMaster University, Canada) was the most prolific with leading academic influence, while Lieb R (University of Basel, Switzerland) and Wittchen HU (Technical University Dresden, Germany) were the most cited authors. The American Journal of Psychiatry (impact factor = 17.7, 2023) was the most frequently cited journal. Furthermore, significant overlapping between premenstrual syndrome and premenstrual dysphoric disorder warrants further investigation, and the intrinsic connection between premenstrual dysphoric disorder and bipolar disorder is a rising focus. Temporally, research shifted from prevalence surveys to diagnostic and mechanistic studies. Conclusions: This bibliometric study comprehensively analyzes the current state of research on physical and mental health comorbidities. North America became a prominent leader in contributions from countries, institutions, authors, and journals. Additionally, the study underscores the potential for further exploration of comorbidity between physiological and psychiatric conditions, suggesting a promising avenue for future research efforts.

Reproduced under CC-BY.

Topics