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Review, 2025

How does the menstrual cycle affect psychiatric symptoms like depression and anxiety?

Many women experience worsening psychiatric symptoms during the premenstrual and menstrual phases due to hormonal changes in estrogen and progesterone. Treatment should monitor symptoms across the menstrual cycle and may include lifestyle changes, therapy, antidepressants, or hormonal therapies.

Early or limited evidence Not applicable - this is a literature review.

What they did

Literature review examining how menstrual cycle phases affect various psychiatric disorders including depression, anxiety, bipolar disorder, and schizophrenia in women.

What they found

Many women report increased severity of psychiatric symptoms during specific menstrual cycle phases. Both hormonal and psychosocial factors contribute to heightened vulnerability during these phases.

What it means for you

Understanding the connection between menstrual cycle and psychiatric symptoms helps improve diagnosis and treatment planning. This is a review article summarizing existing knowledge rather than a new research study.

About the study

Original title
Unmasking the cycle: Premenstrual and menstrual exacerbation of psychiatric disorders and impact on female mental health
Authors
Mazza M, Marano G
Journal
World journal of psychiatry
Year
2025
Study design
Review
What was tested
Not applicable - literature review.
Open access
Yes

Topics