Case-control study, 1998
Are hormone levels different in women with PMS?
Yes, women with PMS had significantly lower progesterone and allopregnanolone levels during the follicular phase of their cycle compared to controls.
What they did
Case-control study measuring levels of the progesterone metabolites allopregnanolone and progesterone in women with PMS and control women.
What they found
Significantly lower levels of both progesterone and allopregnanolone were found in PMS patients in the follicular phase only.
What it means for you
This suggests women with PMS may process progesterone differently than others, at least during the first part of their menstrual cycle. However, the abstract does not provide the specific values of these levels or state how many women were studied, which limits what we can conclude.
About the study
- Original title
- Allopregnanolone in women with premenstrual syndrome
- Authors
- Bicíková M, Dibbelt L, Hill M et al.
- Journal
- Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
- Year
- 1998
- Study design
- Case-control study
- What was tested
- None (observational measurement study)
- Read the paper
- doi.org/10.1055/s-2007-978871
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