Review, 2022
What causes PMDD and what are the best treatments?
PMDD is caused by hormonal changes in estrogen and progesterone that lower serotonin levels. Antidepressants called SSRIs are the most effective treatment, working faster for PMDD than for depression, and women don't necessarily need to take them daily.
What they did
Literature review examining the causes and treatments of PMDD, with focus on hormonal and serotonin mechanisms.
What they found
PMDD involves cyclical changes in estrogen and progesterone causing drops in serotonin. SSRIs are the best treatment and work faster for PMDD than for major depression. Hormone therapies are secondary options. Diet and lifestyle changes may also help with symptom relief.
What it means for you
SSRIs are an effective and relatively quick-acting treatment option for PMDD. This is a review article summarizing existing knowledge rather than a new research study.
About the study
- Original title
- AN OVERVIEWOF THE PATHOPHYSIOLOGY AND TREATMENT OF PREMENSTRUAL DYSPHORIC DISORDER
- Authors
- Pallavi Singh, A.Sowndarya Valli, J. Sujana et al.
- Journal
- Journal of Pharmaceutical Negative Results
- Year
- 2022
- Study design
- Review
- What was tested
- Not applicable - literature review.
- Open access
- Yes
- Read the paper
- doi.org/10.47750/pnr.2022.13.s09.203
Topics
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