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Randomised trial, 1989

Does calcium help PMS?

Yes, likely. Seventy-three percent of women reported fewer symptoms during calcium treatment, and symptom scores dropped significantly during both the luteal and menstrual phases on calcium compared to placebo.

Moderate study design 33 women with moderate to severe PMS who completed the trial

What they did

Randomized double-blind crossover trial. Seventy-eight women were screened and 33 completed the trial. Each woman received three months of daily calcium supplementation (1,000 mg) and three months of placebo in random order. Symptoms were tracked daily.

What they found

Calcium significantly reduced symptoms during the luteal phase (p=0.011) and menstrual phase (p=0.032). Seventy-three percent reported fewer symptoms on calcium, 15% preferred placebo, and 12% had no clear preference. Calcium specifically improved negative affect, water retention, and pain in the luteal phase, and pain during the menstrual phase.

What it means for you

Calcium is simple, affordable, and appears to work for PMS, especially for mood, bloating, and pain. The main limits are that only 33 women completed the study and more research is needed to understand how it works and the right dose.

1,000

Mg of calcium carbonate per day

73

Percentage reporting fewer symptoms on calcium

33

Women who completed the trial

About the study

Original title
Calcium supplementation in premenstrual syndrome: a randomized crossover trial
Authors
Thys-Jacobs S, Ceccarelli S, Bierman A et al.
Journal
Journal of general internal medicine
Year
1989
Study design
Randomised trial
What was tested
Calcium carbonate 1,000 mg per day for three months

Topics