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Survey study, 2010

Do women in different menstrual phases respond to stress differently than men?

Yes. Men showed stronger hormonal stress responses than women. However, women in the luteal phase reported feeling more stressed and showed greater emotional stress hormone responses than women in the follicular phase.

Early or limited evidence 28 men, 29 follicular-phase women, and 23 luteal-phase women

What they did

Tested 28 men and women in two menstrual phases (29 in the follicular phase, 23 in the luteal phase) using a standardized stress test. Measured stress hormones in saliva and blood.

What they found

Men had greater cortisol responses to stress than women in either phase. Luteal women reported the greatest subjective feelings of stress and showed greater allopregnanolone responses. Follicular women showed reduced noradrenaline responses to stress. People who felt stress most intensely also showed larger hormone responses to stress.

What it means for you

Men's bodies respond more strongly to stress with certain hormones, but women in the luteal phase feel stressed more intensely emotionally. This suggests the menstrual cycle changes how both body and mind react to stress. This is a laboratory study using a single artificial stressor, so real-world stress reactions may differ.

28

men

29

follicular-phase women

23

luteal-phase women

About the study

Original title
Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase
Authors
Childs E, Dlugos A, De Wit H
Journal
Psychophysiology
Year
2010
Study design
Survey study
Participants
29
What was tested
Trier Social Stress Test and control task
Open access
Yes

Topics