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Lab study, 1991

Does the central nervous system work differently in women with PMS?

Yes. Women with PMS showed clear differences in brain wave patterns compared to healthy women, with abnormal patterns in the brain stem (46%), hypothalamus (37%), or both (17%).

Early or limited evidence 30 healthy women and 15 women with PMS

What they did

Measured brain waves in 30 healthy women and 15 with PMS using an electroencephalogram at different times in their menstrual cycle.

What they found

Women with PMS had abnormal brain wave patterns different from healthy women. Among those with PMS, 46% showed changes in the brain stem, 37% showed changes in the hypothalamus, and 17% showed changes in both areas. Their brains' adaptive mechanisms were already activating even early in the cycle, indicating these mechanisms were not working properly.

What it means for you

The brain may work differently in people with PMS, particularly in regions that control basic functions and hormones. However, the study was very small (15 women with PMS) and only measured brain waves, not actual symptoms. It doesn't explain how these brain differences relate to what women actually feel.

30

healthy women studied

15

women with PMS studied

46%

with brain stem changes

About the study

Original title
[Characteristics of the functional state of the central nervous system in women during the menstrual cycle and in premenstrual syndrome]
Authors
Tkachenko NM, Smetnik VP, Il'ina EM
Journal
Akusherstvo i ginekologiia
Year
1991
Study design
Lab study
Participants
30

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