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Case report, 2010

Does black cohosh cause blood clots and fluid retention?

One woman using black cohosh developed blood clots, fluid retention, and liver inflammation. This is rare, but doctors should consider it in women with these symptoms who are using black cohosh.

Early or limited evidence Woman using black cohosh for menopausal symptoms

What they did

Case report describing one woman who used black cohosh for menopausal symptoms and developed serious side effects.

What they found

She developed coagulation activation (blood clot formation), fluid retention in her lower legs, and transient liver inflammation.

What it means for you

Black cohosh is usually well tolerated. However, it can occasionally cause serious complications including blood clots and leg swelling. Women using black cohosh who develop leg swelling should seek medical attention. This is based on one case, so we don't know how often this happens.

1

case reported

About the study

Original title
Coagulation activation and fluid retention associated with the use of black cohosh: a case study
Authors
Zimmermann R, Witte A, Voll RE et al.
Journal
Climacteric : the journal of the International Menopause Society
Year
2010
Study design
Case report
What was tested
Black cohosh

Topics