Randomised trial, 2017

What do we currently know about PMDD?

PMDD is increasingly recognized as a serious diagnosis affecting 3-8% of women. We understand its symptoms and how to diagnose it, but we don't yet have enough high-quality research to recommend evidence-based treatments.

Early or limited evidence Not applicable. This is a literature review.

What they did

This is a summary of current knowledge about PMDD that reviews what is known about diagnosis, epidemiology, possible causes, and treatment options.

What they found

PMDD is characterized by emotional, physical, and behavioral changes during the premenstrual phase that cause significant distress and impaired functioning. The 12-month prevalence is 3-8% among women of reproductive age. PMDD was added as a new diagnostic category in the DSM-5 (the official psychiatric diagnostic manual) under depressive disorders. However, it is not yet included in the ICD-10, another international diagnostic system. The underlying mechanisms are still not well understood and likely involve multiple factors.

What it means for you

PMDD is increasingly recognized as a serious condition worthy of its own diagnosis separate from other mood disorders. However, there is still a significant lack of randomized controlled trials in women with PMDD, making it difficult for doctors to recommend evidence-based treatments. More research is needed to understand what causes PMDD and what treatments work best.

3-8%

Percentage of women affected

DSM-5

Diagnostic manual that now includes PMDD

luteal phase

When PMDD symptoms occur

About the study

Original title: [Current Aspects of Premenstrual Dysphoric Disorder - A Review]
Authors: Beddig T, Kühner C
Journal: Psychotherapie, Psychosomatik, medizinische Psychologie
Year: 2017
Study design: Randomised trial
What was tested: Not applicable. This is a literature review.
Read the paper: doi.org/10.1055/s-0043-113816

Topics

Premenstrual dysphoric disorder (PMDD)Menstrual cycle and mood Low mood and depression Major depressive disorder

Cohort study, 2026

What genetic factors are linked to premenstrual symptoms?

Randomised trial, 2025

Does taking an antidepressant only during the second half of your cycle reduce anger and aggression in PMDD?

Systematic review, 2023

Is PMDD linked to depression?

Randomised trial, 2000

Does sertraline improve how women with PMDD feel and function?

Study, 2026

Do anxiety and depression get worse before your period if you already have a mental health condition?