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Case report, 1993

Can psychotic symptoms be linked to the menstrual cycle?

Yes. This girl developed psychotic symptoms that appeared right before her period and disappeared when her period started, suggesting a link to the menstrual cycle. This is a single case.

Early or limited evidence 1 girl aged 14 with PMS

What they did

A 14-year-old girl with PMS who developed psychotic symptoms during two premenstrual periods was treated with dehydroxyprogesterone for two cycles, then placebo for three cycles.

What they found

Her psychotic symptoms resolved completely when her period started in both cases. The symptoms did not return after the two cycles when she had them. Her PMS also resolved in the next cycle.

What it means for you

Psychotic symptoms linked to the menstrual cycle might be a rare condition on its own. We cannot know from this single case whether it happens in other people or how common it is.

1

girl studied

14

age in years

2

menstrual cycles with psychotic symptoms

About the study

Original title
Cyclic psychosis associated with the menstrual cycle
Authors
Stein D, Hanukoglu A, Blank S et al.
Journal
The British journal of psychiatry : the journal of mental science
Year
1993
Study design
Case report
What was tested
Dehydroxyprogesterone for two cycles, then placebo for three cycles

Topics