Skip to content

Randomised trial, 2017

Does the menstrual cycle affect cortisol levels or cigarette craving during smoking abstinence?

The menstrual cycle did not affect cortisol levels during early smoking abstinence. However, cigarette craving behaved differently in different phases. It increased early in the follicular phase but decreased during the luteal phase.

Moderate study design 125 smokers, average age 29.4 years, smoking about 12.6 cigarettes per day

What they did

Secondary analysis of a controlled crossover trial. 125 smokers were tested during both the follicular and luteal phases of their menstrual cycle. In each phase, they smoked normally for 2 days, then abstained from smoking for 4 days. Saliva cortisol and mood were measured multiple times.

What they found

Cortisol decreased when smoking stopped, but this happened the same way in both menstrual phases. Cigarette craving increased in the first day of abstinence during the follicular phase but decreased during the luteal phase.

What it means for you

The menstrual cycle does not change how cortisol responds to smoking abstinence in the first few days. However, the cycle may affect cigarette craving differently. Women might find quitting harder early in their cycle (follicular phase) and easier in the later phase (luteal phase). The study only examined the first few days of abstinence.

125

smokers studied

29.4 ± 0.6

average age in years

12.6 ± 0.5

average cigarettes per day

About the study

Original title
Differences in mood and cortisol by menstrual phase during acute smoking abstinence: A within-subject comparison
Authors
Carlson SC, Allen AM, Allen SS et al.
Journal
Experimental and clinical psychopharmacology
Year
2017
Study design
Randomised trial
Participants
125
What was tested
4 days of smoking abstinence following 2 days of normal smoking
Open access
Yes

Topics