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Review, 2007

Is drospirenone an effective ingredient in birth control pills for PMDD?

Birth control pills containing drospirenone appear safer and better tolerated than other low-dose pills for mood changes, acne, and severe PMS (PMDD), with similar overall safety profiles.

Early or limited evidence Women taking oral contraceptives and hormone therapy (specific numbers not given)

What they did

Review of drospirenone in combined oral contraceptives and hormone therapy, examining how well it works and how safe it is.

What they found

Drospirenone has special properties that block androgen and mineral effects. Pills with drospirenone had similar effectiveness and safety to other low-dose pills but showed better tolerability, including less weight gain, better mood, clearer skin, and better treatment of PMDD.

What it means for you

Drospirenone may be a better choice for women with PMDD and acne, but this is a review without new effectiveness numbers provided.

About the study

Original title
Drospirenone: a novel progestin
Authors
Rapkin AJ, Winer SA
Journal
Expert opinion on pharmacotherapy
Year
2007
Study design
Review
What was tested
Drospirenone-containing contraceptives and hormone therapy

Topics