Case-control study, 2025
Does sleep quality affect brain activity and anxiety-depression symptoms in PMS?
Yes. Poor sleep quality in PMS patients is linked to different brain activity patterns. The relationship between certain brain changes and anxiety-depression symptoms is partly explained by sleep quality.
What they did
Case-control study comparing 77 PMS patients and 66 healthy people. Participants had brain imaging (fMRI) and completed questionnaires about sleep quality, anxiety, and depression.
What they found
PMS patients with poor sleep had different brain connectivity patterns than those with normal sleep. Both PMS groups showed some abnormal brain connections compared to healthy controls. The link between brain changes in certain areas and anxiety-depression was partly mediated by sleep quality.
What it means for you
Sleep quality may be important in how brain changes cause anxiety and depression in PMS. If confirmed, improving sleep might help reduce these symptoms. The study was observational and only showed associations, not causation.
77
PMS patients studied
66
healthy controls studied
About the study
- Original title
- Effects of sleep quality on the default mode network and on anxiety-depression symptoms in premenstrual syndrome
- Authors
- Qin H, Zhang Y, Li S et al.
- Journal
- BMC psychiatry
- Year
- 2025
- Study design
- Case-control study
- What was tested
- None - observational study
- Open access
- Yes
- Read the paper
- doi.org/10.1186/s12888-025-07126-2
Topics
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