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Review, 2010

Which genes are involved in menstrual migraine?

Menstrual migraine involves genetics, hormones, and environment, but the specific genes responsible remain unclear. This review discusses the evidence and suggests future research directions.

Early or limited evidence Review of genetic studies on menstrual migraine

What they did

Literature review of candidate gene studies and molecular evidence on how reproductive hormones might influence genes in migraine.

What they found

The review notes that female sex hormones' role in migraine is well established, but the genetic mechanism remains unclear. The review identifies challenges in interpreting hormone-related gene results and discusses future research approaches.

What it means for you

Genetics likely contributes to menstrual migraine, but researchers don't yet know which specific genes matter and how they interact with hormones. More research with better methods is needed.

About the study

Original title
Genetics of menstrual migraine: the molecular evidence
Authors
Colson N, Fernandez F, Griffiths L
Journal
Current pain and headache reports
Year
2010
Study design
Review
What was tested
None
Open access
Yes

Topics