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Cohort study, 2026

Does cannabis use vary across the menstrual cycle in people with premenstrual disorders?

Yes, the amount of cannabis used peaks before menstruation and around ovulation in people with premenstrual disorders. The pattern is stronger when emotional symptoms worsen.

Moderate study design Naturally cycling individuals with diagnosed or suspected premenstrual disorders

What they did

People with diagnosed or suspected premenstrual disorders were followed for 2 to 3 menstrual cycles. They recorded daily cannabis use and premenstrual symptom severity each day using a standardized symptom tracker.

What they found

Daily cannabis quantity showed a pattern across the menstrual cycle, peaking before menstruation onset and around ovulation (p = 0.030). Emotional symptoms like feeling rejected and relationship problems made this pattern stronger (p = 0.004 for emotional symptoms, p = 0.010 for interpersonal conflicts). Higher-than-usual emotional symptoms were linked to more cannabis use before menstruation.

What it means for you

Cannabis use in people with premenstrual disorders tracks with the menstrual cycle and emotional symptoms. This could help inform prevention and treatment strategies. The sample size is not clearly described, which limits interpretation.

2-3

menstrual cycles tracked per person

p = 0.030

menstrual cyclicity of cannabis quantity

p = 0.004

emotional symptoms moderation effect

About the study

Original title
Menstrual cyclicity of cannabis use: a longitudinal study using phase-aligned cycle time scaling (PACTS)
Authors
Zorzini G, Ly M, Wahl T et al.
Journal
Addictive behaviors
Year
2026
Study design
Cohort study
What was tested
Observational tracking of cannabis use and premenstrual symptoms
Open access
Yes

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