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Review, 2000

What conditions beyond depression can antidepressants treat?

Newer antidepressants including SSRIs have FDA approval for several conditions including anxiety, obsessive-compulsive disorder, and panic disorder. Controlled studies also show they help premenstrual dysphoric disorder.

Moderate study design Various populations studied in controlled trials, including people with premenstrual dysphoric disorder

What they did

This was a review of FDA approvals and controlled research on newer antidepressants for various conditions beyond major depression.

What they found

Some newer antidepressants have FDA approval for generalized anxiety disorder, bulimia nervosa, obsessive-compulsive disorder, social phobia, panic disorder, and posttraumatic stress disorder. In controlled studies, these agents also showed effectiveness in premenstrual dysphoric disorder, borderline personality disorder, obesity, smoking cessation, and alcoholism.

What it means for you

Antidepressants are useful for treating many conditions beyond depression, including PMDD. However, this is a review of evidence rather than a single study, and individual responses to medication vary.

About the study

Original title
New indications for antidepressants
Authors
Schatzberg AF
Journal
The Journal of clinical psychiatry
Year
2000
Study design
Review
What was tested
Various antidepressant medications (reviewed evidence)

Topics